Cell mechanics in early vertebrate development:Yap mechanotransduction controls notochord formation and neural tube patterning  

作　　者：Zheng Guo Jing Du 

机构地区：[1]Key Laboratory of Biomechanics and Mechanobiology(Beihang University),Ministry of Education Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical Engineering,Beihang University,Beijing,100083,China

出　　处：《Mechanobiology in Medicine》2023年第2期11-12,共2页力学生物学与医学（英文）

摘　　要：A recent study published in Science Advances1 showed the influence of Yap on notochord formation and NT(neural tube)patterning in vertebrate embryonic development,and conducted an in-depth study from the perspective of biomechanical signal mechanotransduction.In addition,this study also explored the possible complex interaction between mechanical signals and gene expression.Together,this study provides new insights into the development mechanism of early vertebrate embryos.

关 键 词：Yap TAZ Embryonic development MECHANOTRANSDUCTION NOTOCHORD Neural tube 

分 类 号：R318[医药卫生—生物医学工程]