A recent study published in Science Advances1 showed the influence of Yap on notochord formation and NT(neural tube)patterning in vertebrate embryonic development,and conducted an in-depth study from the perspective o...
This work was supported by the Gusu Health Talent Project of Suzhou(Grant No.GSWS2020056);“333”Talent Project of Jiangsu Province(Grant No.BRA2017057).
Transcription factor Brachyury,a protein containing 435 amino acids,has been widely investigated and reported in notochord differentiation and nucleus pulposus development.The crucial functions and underlying mechanis...
Jason W.Ashley,PhD is supported by the University of Pennsylvania Postdoctoral Opportunities in Research and Teaching(PENN-PORT)fellowship funded by the National Institute of General Medical Sciences Institutional Research and Career Development Award(IRACDA;5 K12 GM081259-09);Yejia Zhang,MD,PhD has been supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development(NICHD,1K08 HD049598);This work is supported,in part,by research grants from the Department of Veterans Affairs(VA RR&D I01 RX001321 and VA1I21RX001896);the Research Grants Committee of Hong Kong(T-12-708/12N).
The intervertebral disc(IVD)comprises a gelatinous inner core(nucleus pulposus;NP)and concentric rings(annulus fibrosus;AF).The NP,an important structure for shock absorption in the vertebrate spinal motion segment,ca...
Aim: To describe the clinical, anatomical, therapeutic aspects and propose a diagram of a new type of a complete urethral duplicity in classification of Effman. Material and Methods: This was a case report of a 14-yea...
Ecchordosis physaliphora (EP) is a benign congenital hamartoma of the ectopic notochordal remnant, accounting for 0.5-2% of all autopsies, and found in 1.5% of all magnetic resonance imaging (MRI) of the brain. It...
Klippel-Feil syndrome(KFS) is defined by congenital cervical vertebral spine fusion and is seen with a wide spectrum of dental manifestations and craniofacial profiles. Previous studies on lateral cephalograms have do...
supported by the National Natural Science Foundation of China(No.21277049);the State Key Laboratory of Estuarine and Coastal Research(No.2012KYYW04)
Xenopus tropicalis embryos were exposed for 48 hr to the mixtures of 5 μg Sn/L triphenyltin (TPT), which is a well-known endocrine disruptor, and 0.25-5 μg/L 9-cis retinoic acid (9c-RA), which is the natural lig...
The nasopharynx is an unusual site for extraosseous chordoma. The characteristic histology and immunohistochemistry confirmed the diagnosis. The behaviour of this tumour is locally aggressive. We report a case of naso...
Due to the rare occurrence of chordomas extra-axially, these lesions have not earned a great deal of consideration in the clinical and radiographic differential diagnoses of extra-axial paraspinal lesions. We describe...