NOTOCHORD

作品数:11被引量:5H指数:1
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相关领域:生物学更多>>
相关机构:东南大学徐州医学院附属医院更多>>
相关期刊:《Open Journal of Urology》《Mechanobiology in Medicine》《医用生物力学》《Genes & Diseases》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Yap Controls Notochord Formation and Neural Tube Patterning by Integrating Mechanotransduction with FoxA2 and Shh Expression
《医用生物力学》2024年第S01期604-604,共1页程才奇 Yingzi Yang 
目的正确的脊索和神经管(NT)形成对于中枢神经系统的发育至关重要。在胚胎发育中,生物力信息不断被胚胎细胞收集,生化和生物物理信号控制着胚胎的生长和模式化。然而,目前对生物信号的功能以及其与生物物理刺激是如何相互作用的仍知之...
关键词:生物物理 神经管 中枢神经系统 萤光素酶报告基因 外植体培养 机械刺激 胚胎细胞 生物信号 
Cell mechanics in early vertebrate development:Yap mechanotransduction controls notochord formation and neural tube patterning
《Mechanobiology in Medicine》2023年第2期11-12,共2页Zheng Guo Jing Du 
A recent study published in Science Advances1 showed the influence of Yap on notochord formation and NT(neural tube)patterning in vertebrate embryonic development,and conducted an in-depth study from the perspective o...
关键词:Yap TAZ Embryonic development MECHANOTRANSDUCTION NOTOCHORD Neural tube 
The role of transcriptional factor brachyury in the development and repair of nucleus pulposus
《BIOCELL》2022年第6期1363-1364,共2页YINGHUI WU HONG ZHANG QIANG WANG SUOYUAN LI JUN SHEN 
This work was supported by the Gusu Health Talent Project of Suzhou(Grant No.GSWS2020056);“333”Talent Project of Jiangsu Province(Grant No.BRA2017057).
Transcription factor Brachyury,a protein containing 435 amino acids,has been widely investigated and reported in notochord differentiation and nucleus pulposus development.The crucial functions and underlying mechanis...
关键词:BRACHYURY Nucleus pulposus NOTOCHORD IVD 
Intervertebral disc development and disease-related genetic polymorphisms被引量:3
《Genes & Diseases》2016年第3期171-177,共7页Jason W.Ashley Motomi Enomoto-Iwamoto Lachlan J.Smith Robert L.Mauck Danny Chan Joseph Lee Martin F.Heyworth Howard An Yejia Zhang 
Jason W.Ashley,PhD is supported by the University of Pennsylvania Postdoctoral Opportunities in Research and Teaching(PENN-PORT)fellowship funded by the National Institute of General Medical Sciences Institutional Research and Career Development Award(IRACDA;5 K12 GM081259-09);Yejia Zhang,MD,PhD has been supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development(NICHD,1K08 HD049598);This work is supported,in part,by research grants from the Department of Veterans Affairs(VA RR&D I01 RX001321 and VA1I21RX001896);the Research Grants Committee of Hong Kong(T-12-708/12N).
The intervertebral disc(IVD)comprises a gelatinous inner core(nucleus pulposus;NP)and concentric rings(annulus fibrosus;AF).The NP,an important structure for shock absorption in the vertebrate spinal motion segment,ca...
关键词:Back pain DEVELOPMENT Intervertebral disc(IVD) NOTOCHORD REGENERATION 
Complete Urethral Duplicity: A Rare Cause of Urinary Incontinence, New Type According to Effman’s Classification
《Open Journal of Urology》2015年第10期182-187,共6页Kimassoum Rimtebaye Franklin Danki Sillong Arya Zarif Agah Tashkand Mignagnal Kaboro Lamine Niang Serigne Magueye Gueye 
Aim: To describe the clinical, anatomical, therapeutic aspects and propose a diagram of a new type of a complete urethral duplicity in classification of Effman. Material and Methods: This was a case report of a 14-yea...
关键词:URETHRAL Duplication EPISPADIAS PENIS KINKING NOTOCHORD SPHINCTER 
Multiple Ecchordosis Physaliphora: A Challenging Diagnosis被引量:1
《Chinese Medical Journal》2015年第20期2826-2828,共3页Xiao-Ling Zhong Biao Huang Chao Liu Sheng-Quan Zhan 
Ecchordosis physaliphora (EP) is a benign congenital hamartoma of the ectopic notochordal remnant, accounting for 0.5-2% of all autopsies, and found in 1.5% of all magnetic resonance imaging (MRI) of the brain. It...
关键词:Ecchordosis Physaliphora Magnetic Resonance Imaging NOTOCHORD PATHOLOGY SURGERY 
Klippel-feil:A syndrome in the occipital-cervical spine field and its dentofacial manifestations被引量:1
《World Journal of Stomatology》2015年第2期81-86,共6页Trine G Michelsen Pernille B Brusgaard Liselotte Sonnesen 
Klippel-Feil syndrome(KFS) is defined by congenital cervical vertebral spine fusion and is seen with a wide spectrum of dental manifestations and craniofacial profiles. Previous studies on lateral cephalograms have do...
关键词:Occipital and cervical spine field Klippel-Feil syndrome NOTOCHORD EMBRYOLOGY Cervical column morphology MALOCCLUSION 
Unexpected phenotypes of malformations induced in Xenopus tropicalis embryos by combined exposure to triphenyltin and 9-cis-retinoic acid
《Journal of Environmental Sciences》2014年第3期643-649,共7页Jingmin Zhu Lin Yu Lijiao Wu Lingling Hu Huahong Shi 
supported by the National Natural Science Foundation of China(No.21277049);the State Key Laboratory of Estuarine and Coastal Research(No.2012KYYW04)
Xenopus tropicalis embryos were exposed for 48 hr to the mixtures of 5 μg Sn/L triphenyltin (TPT), which is a well-known endocrine disruptor, and 0.25-5 μg/L 9-cis retinoic acid (9c-RA), which is the natural lig...
关键词:Xenopus tropicalis embryos triphenyltin teratogenicity retinoic acid notochord 
Chordoma in Nasopharynx in a 70-Year-Old Female: A Rare Occurence
《International Journal of Otolaryngology and Head & Neck Surgery》2014年第6期342-346,共5页Bhaskar Mitra Subhalakshmi Sengupta Anshita Rai Jay Mehta Aruna Rai Quader Subhendu Roy Anita Borges 
The nasopharynx is an unusual site for extraosseous chordoma. The characteristic histology and immunohistochemistry confirmed the diagnosis. The behaviour of this tumour is locally aggressive. We report a case of naso...
关键词:CHORDOMA NASOPHARYNGEAL Tumours NOTOCHORD 
Chordomas and Their Consideration in the Radiographic Differential of Extra-Axial Lesions of the Central Nervous
《Open Journal of Modern Neurosurgery》2012年第3期58-62,共5页Shih-Shan Lang Jayesh P. Thawani Anousheh Sayah Sriram Venneti Danielle Brewington Eric L. Zager Stephen J. Dante 
Due to the rare occurrence of chordomas extra-axially, these lesions have not earned a great deal of consideration in the clinical and radiographic differential diagnoses of extra-axial paraspinal lesions. We describe...
关键词:CHORDOMA Primitive NOTOCHORD TUMOR Extra-Axial TUMOR Spine 
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