Chordomas and Their Consideration in the Radiographic Differential of Extra-Axial Lesions of the Central Nervous  

作　　者：Shih-Shan Lang Jayesh P. Thawani Anousheh Sayah Sriram Venneti Danielle Brewington Eric L. Zager Stephen J. Dante 

机构地区：[1]Department of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, USA [2]Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania Medical Center, Philadelphia, USA [3]Department of Radiology, Georgetown University Hospital, Washington DC, USA [4]Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA

出　　处：《Open Journal of Modern Neurosurgery》2012年第3期58-62,共5页现代神经外科学进展（英文）

摘　　要：Due to the rare occurrence of chordomas extra-axially, these lesions have not earned a great deal of consideration in the clinical and radiographic differential diagnoses of extra-axial paraspinal lesions. We describe a case of a patient with a surgically resected extra-axial chordoma and review the radiologic characteristics of chordomas as an entity in the spectrum of extra-axial lesions. A 47-year-old man presented to our institution with four months of intermittent parethesias, pain, and subjective weakness in the left leg. MR imaging of the lumbar spine demonstrated a large heterogeneously- enhancing paraspinal lesion extending from the left L3-4 neural foramen into the psoas muscle. The patient underwent a CT-guided needle biopsy demonstrating features consistent with a chordoma. He then underwent a left retroperitoneal approach and en bloc resection of the lesion from the vertebral column. Pathology confirmed chordoma as the diagnosis. EACs are a rare but important consideration in the diagnosis of extra-axial lesions of the central nervous system.Due to the rare occurrence of chordomas extra-axially, these lesions have not earned a great deal of consideration in the clinical and radiographic differential diagnoses of extra-axial paraspinal lesions. We describe a case of a patient with a surgically resected extra-axial chordoma and review the radiologic characteristics of chordomas as an entity in the spectrum of extra-axial lesions. A 47-year-old man presented to our institution with four months of intermittent parethesias, pain, and subjective weakness in the left leg. MR imaging of the lumbar spine demonstrated a large heterogeneously- enhancing paraspinal lesion extending from the left L3-4 neural foramen into the psoas muscle. The patient underwent a CT-guided needle biopsy demonstrating features consistent with a chordoma. He then underwent a left retroperitoneal approach and en bloc resection of the lesion from the vertebral column. Pathology confirmed chordoma as the diagnosis. EACs are a rare but important consideration in the diagnosis of extra-axial lesions of the central nervous system.

关 键 词：CHORDOMA Primitive NOTOCHORD TUMOR Extra-Axial TUMOR Spine 

分 类 号：R73[医药卫生—肿瘤]