Penpulimab is an anti-programmed cell death-1(PD-1)IgG1 antibody with no Fc gamma receptor(FcγR)binding activity,and thus theoretically reduced immune-related adverse events(irAEs)while maintaining efficacy.This sing...
supported by the National Key R&D Program of China(2022YFA1204000 to T.D.);the Guangdong Key Area Research and Development Program(2019B020228001 to T.D.);the National Natural Science Foundation of China(81971906 to T.D.).
Nasopharyngeal carcinoma(NPC)is a malignancy originating from the nasopharyngeal epithelial cells.Although some studies have identified potential biomarkers for early diagnosis of NPC based on metabolomics data(Chen e...
Nasopharyngeal liposarcoma is an extremely rare clinical entity. Less than ten cases have been reported in the literature. It mainly occurs in humans. The non-specificity of the clinical and radiological signs explain...
supported by the National Key Research and Development Program of China(2021YFC2500400);the National Natural Science Foundation of China(81802708);the Key Area Research and Development Program of Guangdong Province,China(2019B110233004);the Science and Technology Planning Project of Guangdong Province,China(2019B030316031).
Nasopharyngeal carcinoma(NPC),a highly invasive and metastatic cancer,is widely prevalent in South China,Southeast Asia,and North Africa.NPC patients with stages I and II are often asymptomatic.Therefore,NPC patients ...
supported by the National Natural Science Foundation of China(Nos 92169212 and 82161138018);Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response(20dz2260100);Key Discipline Construction Plan fromShanghaiMunicipalHealth Commission(GWV-10.1-XK01);ShanghaiMunicipal Science and Technology Major Project(HS2021SHZX001).
The Omicron variants have continued to cause severe acute respiratory syndrome coronavirus 2 infections.To better understand the anti-viral effects of vaccination on host-virus interactions during the outbreak of BA.2...
Patients with nasopharyngeal carcinoma(NPC)represent a distinct group of head and neck cancer patients.They are often non-smokers,non-drinkers,and on average 10 to 20 years younger than those with cancers of other hea...
supported by the National Natural Science Foundation of China(Grant Nos.81902506,81930084).
Dear Editor,The pathogenesis of nasopharyngeal carcinoma(NPC)is closely associated with the infection of Epstein Barr virus(EBV)(Hau et al.,2020).However,the mechanisms underlying NPC tumorigenesis remain unclear,lead...
the National Natural Science Foundation of China(82172749);the Natural Science Foundation of Guangdong Province(2021B1515020010);the Fundamental Research Funds for the Central Universities,Sun Yat-sen University(22ykqb14).
1 BACKGROUND Nasopharyngeal carcinoma(NPC)is a unique head and neck malignancy prevalent in East Asia[1].It is highly malignant,with the non-keratinizing pathological subtype constituting approximately 95%of NPC cases...
The Hong Kong Nasopharyngeal Carcinoma(NPC)Study Group 0501 trial(HK0501)is the first trial that directly compares induction(IC)versus adjuvant chemotherapy(AC)both given together with concurrent chemoradiation(CCRT)t...