Effects of ultrasound-assisted Fenton treatment on structure and hypolipidemic activity of apricot polysaccharides  

作　　者：Kaiqian Xu Jinfeng dou Caie Wu Gongjian Fan Xiaojing Li Wenjuan Sun Andi Suo Zhentian Li Lanmei Zhang 

机构地区：[1]College of Light Industry and Food Engineering,Nanjing Forestry University,Nanjing,Jiangsu,210037,PR China [2]Co-Innovation Center of Efficient Processing and Utilization of Forest Resources,Nanjing Forestry University,Nanjing,210037,China [3]College of Life and Health Sciences,Anhui Science and Technology University,Fengyang,233100,China

出　　处：《Food Bioscience》2022年第6期892-901,共10页食品生物科学（英文）

基　　金：supported by National Key R&D Program of China(2019YFD1002300);the North Jiangsu Science and Technology Project(XZ-SZ201929);the Research Project of Jiangxi Forestry Bureau(No.202012).

摘　　要：In order to improve the hypolipidemic activity of apricot polysaccharide,the methods of modifying polysaccharide were preliminarily screened,and the modification process conditions were further optimized by response surface methodology.Subsequently,the structure characterization and hypolipidemic activity of polysaccharide obtained by ultrasound-assisted Fenton treatment(EAP-UF)were studied.The results of Box-Behnken design indicated that under the optimal conditions of ultrasound-assisted Fenton degradation,the binding rate of sodium taurocholate and sodium glycocholate were 62.10%and 59.87%,respectively.Furthermore,the molecular weight,particle size,PDI value and roughness of EAP-UF decreased obviously,while the contents of hydroxyl,carbonyl carboxyl and rhamnose increased obviously.What's more,EAP-UF could significantly reduce the content of fat accumulation,triglyceride and total cholesterol in Caenorhabditis elegans.Taken together,ultrasound-assisted Fenton treatment is an effective method to enhance the hypolipidemic activity of polysaccharides.

关 键 词：ULTRASOUND Fenton reaction APRICOT POLYSACCHARIDE Hypolipidemic activity 

分 类 号：TS201.4[轻工技术与工程—食品科学]