特色发酵类中药竹沥曲炮制工艺研究  

Research on the Processing Technology of Characteristic Fermented Traditional Chinese Medicine Bamboo Juice Medicated Leaven

作　　者：宋佩林 纪奇森 万兴东 徐海英 寿红斌 胡久平 黄勤挽[1] Song Peilin;Ji Qisen;Wan Xingdong;Xu Haiying;Shou Hongbin;Hu Jiuping;Huang Qinwan(College of Pharmacy,Chengdu University of TCM,Chengdu 611137,China;Ya an Xunkang Pharmaceutical Co.,Ltd.,Chengdu 625600,China)

机构地区：[1]成都中医药大学药学院,四川成都611137 [2]雅安迅康药业有限公司,四川成都625600

出　　处：《亚太传统医药》2025年第1期31-37,共7页Asia-Pacific Traditional Medicine

基　　金：四川省中医药管理局课题(2023MS355)。

摘　　要：目的:依据古代文献记载,恢复竹沥曲发酵工艺,优选竹沥曲的现代发酵工艺。方法:利用单因素试验方法,考察发酵温度、发酵时间、发酵湿度,以每日外观性状、酶活力为评价指标,运用综合加权评分法进行最优工艺参数优选。结果:面粉采用干混法,加水量控制在20~30 g,最佳发酵温度40℃,湿度90%,发酵10 d。结论:筛选出的竹沥曲现代发酵工艺参数具有可行性,工艺稳定可靠,重复性好,与古籍文献记载相符合,可为竹沥曲后续深入研究提供参考。Objective:Recovering the fermentation process of Bamboo Juice Medicated Leaven based on ancient literature and optimizing its modern fermentation process parameters.Methods:The study investigated the optimal fermentation temperature,humidity,and time for Bamboo Juice Medicated Leaven using a one-way test.The comprehensive weighted scoring method was then used to screen for the best process parameters based on daily appearance traits and enzyme vigor as evaluation indexes.Results:The flour is mixed dry,and the amount of water added is controlled at 20-30 g.The optimal fermentation conditions are a temperature of 40℃and a humidity of 90%.The fermentation process should last for ten days.Conclusion:The modern fermentation process parameters have been screened and found to be feasible.The process is stable and reproducible,which is consistent with ancient records.It can serve as a reference for Bamboo Juice Medicated Leaven subsequent in-depth research.

关 键 词：竹沥曲 发酵工艺 酶活力 发酵类中药 

分 类 号：R283[医药卫生—中药学]