Allogeneic CAR T cells for autoimmune diseases:a glimpse into the future  

作　　者：Dimitrios Mougiakakos 

机构地区：[1]Department of Hematology,Oncology,and Cell Therapy,Otto-von-Guericke University Magdeburg,Magdeburg,Germany

出　　处：《Signal Transduction and Targeted Therapy》2024年第11期4758-4759,共2页信号转导与靶向治疗（英文）

基　　金：supported by the Deutsche Forschungsgemeinschaft(DFG,project nr.536993790);the European Regional Development Fund(project ZELL-THEMA).

摘　　要：In a recent study published in Cell,Wang X et al.1 reported the first use of allogeneic anti-CD19 CAR T cells in patients with therapyresistant autoimmune diseases,demonstrating their effectiveness in reducing disease activity,with good tolerability and persistence.These findings suggest that allogeneic CAR T cells could offer a scalable,off-the-shelf treatment option for autoimmune disorders.

关 键 词：AUTOIMMUNE DISEASES 

分 类 号：R392[医药卫生—免疫学]