Gut microbial carcinogen metabolism:another avenue to cancer  

作　　者：Florian R.Greten Melek C.Arkan 

机构地区：[1]Institute for Tumor Biology and Experimental Therapy,Georg-Speyer-Haus,Frankfurt/Main,Germany [2]Frankfurt Cancer Institute,Goethe University Frankfurt,Frankfurt/Main,Germany [3]German Cancer Consortium(DKTK)and German Cancer Research Center(DKFZ),Heidelberg,Germany

出　　处：《Signal Transduction and Targeted Therapy》2024年第11期4783-4784,共2页信号转导与靶向治疗（英文）

基　　金：Work in the lab of FRG and MCA is funded by institutional funds from the Georg-Speyer-Haus,the LOEWE Center Frankfurt Cancer Institute(FCI)funded by the Hessen State Ministry for Higher Education,Research and the Arts LOEWE,grants to FRG from the Deutsche Forschungsgemeinschaft(FOR2438:Gr1916/11-1,SFB1292-Project ID:318346496-TP16,SFB1479-Project ID:441891347-P02,GRK2336)the German Federal Ministry of Education;Research(BMBF,01KD2206Q/SATURN3);the European Research Council(Advanced Grant PLASTICAN-101021078).

摘　　要：A recent study published in Nature by Roje,Zhang and colleagues highlights the emergent role gut microbiota play in processing environmental carcinogens and raises its potential as a target for reducing cancer risk in humans.1 This study fills yet another piece into the giant jigsaw puzzle that illustrates the central role of the dynamic structure and function of the intestinal microbiome in cancer pathogenesis and therapy efficacy.

关 键 词：METABOLISM CANCER pathogenesis 

分 类 号：R574[医药卫生—消化系统]