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作 者:LI Tian-tian WU Yan YANG Ying-xin XUE Yu-xin MA Chao-ting
出 处:《Chinese Journal of Integrative Medicine》2025年第1期68-72,共5页中国结合医学杂志(英文版)
摘 要:Hydroxychloroquine(HCQ)is widely used in the treatment of autoimmune disorders such as systemic lupus erythematosus(SLE)and rheumatoid arthritis,and in recent years it has also been used in diseases such as cancer,neurodegenerative diseases,metabolic diseases,and microbial infections.(1)Due to the complex pharmacokinetic characteristics of HCQ,overdose or long-term use of the drug will lead to accumulation in the tissue of organism,and severe HCQ-related retinal toxicity may occur.A cohort study in America showes that after 10 and 15 years of HCQ use,the incidence of HCQ retinopathy will be 2.5%and 8.6%,respectively.(2)The clinical manifestations of HCQ retinopathy are various,mainly photoreceptor and retinal pigment epithelium(RPE)defects,some combined with cystoid macular edema(CME),and ireversible central vision loss.
关 键 词:ACUPUNCTURE DISEASES EPITHELIUM
分 类 号:R276.7[医药卫生—中医五官科学]
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