新型生物传感器在真菌毒素快速检测中的研究进展  

Research Progress of Novel Biosensors in Rapid Detection of Mycotoxins

作　　者：沈文洁 郭宝元 倪保霞 石亚坤 轩志宏 黄凯[2] 刘洪美 Shen Wenjie;Guo Baoyuan;Ni Baoxia;Shi Yakun;Xuan Zhihong;Huang Kai;Liu Hongmei(Academy of National Food and Strategic Reserves Administration,Beijing 100037;School of Health Science and Engineering University of Shanghai for Science and Technology,Shanghai 200093;College of Food Science and Engineering,Henan University of Technology,Zhengzhou 450001)

机构地区：[1]国家粮食和物资储备局科学研究院,北京100037 [2]上海理工大学健康科学与工程学院,上海200093 [3]河南工业大学粮油食品学院,郑州450001

出　　处：《中国粮油学报》2025年第1期225-234,共10页Journal of the Chinese Cereals and Oils Association

基　　金：中国科协青年人才托举工程项目(2021QNRC001),中央级公益性科研院所基本科研业务费专项(ZX2228),国家自然科学基金项目(32202157)。

摘　　要：真菌毒素污染问题已成为世界各国高度关注的食品安全热点问题,严重威胁人畜健康和生态环境安全。快速、精确的真菌毒素快速检测技术对保障食品安全有着重要意义。生物传感器具有操作简单、响应快速、灵敏度高和准确性好等优点,受到越来越多的科研工作者及社会各界人士的青睐。本文综述了近年来新型生物传感器(基于固相载体创新的生物传感器、基于识别元件创新的生物传感器和基于信号放大创新的生物传感器)在真菌毒素检测的研究进展,系统分析了各种生物传感器的构建原理、方法特点和相关应用进展,并提出了面临的挑战与发展趋势,以期为真菌毒素快速检测技术的研究提供参考和启发,同时可为保障粮食安全提供新思路。Mycotoxin contamination has become a hot issue of food safety in the world,it seriously threatens human and animal health and ecological environment safety.Rapid and accurate mycotoxin rapid detection technology is of great significance to ensure food safety.Biosensors have the advantages of simple operation,fast response,high sensitivity and good accuracy,and are favored by more and more researchers and people from all walks of life.In this paper,the research progress of new biosensors(biosensors based on solid-phase carrier innovation,biosensors based on recognition element innovation and biosensors based on signal amplification innovation)in the detection of mycotoxins in recent years was reviewed.The construction principle,method characteristics and related application progress of various biosensors were systematically analyzed,and the challenges and development trends were put forward,in order to provide reference and inspiration for the research of rapid detection technology of mycotoxins,and to provide new ideas for ensuring food security.

关 键 词：真菌毒素 生物传感器技术 快速检测 

分 类 号：TS210.7[轻工技术与工程—粮食、油脂及植物蛋白工程]