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作 者:李沛奕 赵敏[1] LI Peiyi;ZHAO Min(School of Integrative Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China;School of Basic Medical Sciences,Peking University,Beijing 100191,China;The First School of Clinical Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China)
机构地区:[1]南京中医药大学中西医结合学院,南京210023 [2]北京大学基础医学院,北京100191 [3]南京中医药大学第一临床医学院,南京210023
出 处:《中华中医药杂志》2024年第12期6330-6337,共8页China Journal of Traditional Chinese Medicine and Pharmacy
基 金:国家自然科学基金项目(No.82104857,No.82474526);江苏省自然科学基金项目(No.BK20210690);南京中医药大学本科教育教学改革研究课题(No.NZYJG2022003);南京中医药大学国家自然科学基金经费配套项目(No.XPT82104857)。
摘 要:中医千载传承,经典代有充栋。虽古今生产力水平有悬殊差异,但先圣将人和自然相统一的智慧和能力,依然是今人效仿的榜样。义理虽一,古今表述有别。故以“辨”沟通古今。“苦能燥湿”理论源于先圣临床实践的总结,后世运用奉为玉律,且功效卓著。基于《黄帝内经》,借助今世科研成果,以最直白之辞,敢解“苦能燥湿”之旨,冀索玉还。苦者味之一,湿者气之一,气味相作,影响人体津液之稳态。“湿”为组成生命的重要元素之一,亦是疾病的基调。“苦能燥湿”就是“苦”味物质可广泛参与机体神经-体液调节,如通过触动苦味受体这个警示开关,引发级联反应而致机体之“湿”产生相应变化,同时亦可影响意识活动,协同调控生命稳态。Traditional Chinese medicine has been inherited for thousands of years,and the classics have been abundant from generation to generation.Although there is a huge difference in the level of productivity between ancient and modern times,the wisdom and ability of the ancestors to unify man and nature are still an example for people today to follow.Although the meaning and principle are still the same,there are differences between ancient and modern expressions.Therefore,similarities and differences should be analyzed to communicate the past and the present.The theory of‘bitterness can dry dampness’originated from the summary of the clinical practice of ancient doctors,and was used as the standard in later generations,and the effect was outstanding.Based on Huangdi Neijing,and with the help of the results of modern scientific research,explain the connotation of‘bitterness can dry dampness’in the most straightforward language,hoping to get more inspiration.Bitterness is one of the Weis,dampness is one of the Qi,and the Qi and Wei interact with each other,affecting the homeostasis of the body’s fluid metabolism.‘Dampness’is one of the important elements of life and the basis of disease.‘Bitterness can dry dampness’means that bitter taste substances can widely participate in the regulation of nerve-humoral in the body.For example,by triggering the bitter taste receptors,a cascade reaction will be triggered to cause corresponding changes in the dampness of the body,and at the same time,it can also affect the conscious activities and synergistically regulate the homeostasis of life.
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