液相色谱串联质谱法测定猪肉中的兽药残留  

Determination of Veterinary Drug Residues in Pork by Liquid Chromatography-Tandem Mass Spectrometry

作　　者：杨文珺 王华 YANG Wenjun;WANG Hua(Linxia State Food Inspection and Testing Center,Linxia 731100,China;Linxia Livestock Technology Promotion Station,Linxia 731100,China)

机构地区：[1]临夏州食品检验检测中心,甘肃临夏731100 [2]临夏州畜牧技术推广站,甘肃临夏731100

出　　处：《食品安全导刊》2025年第5期106-109,共4页China Food Safety Magazine

摘　　要：为强化猪肉食品安全,采用液相色谱串联质谱法测定猪肉中的兽药残留,重点检测恩诺沙星、环丙沙星、氧氟沙星、莱克多巴胺等6种常见的抗菌药物,对现有检测方法进行优化,并进行方法学评价和实际样品测定。结果表明,改进后的检测方法操作简单、样品回收率更高;35份猪肉样品中,有1份检出恩诺沙星,检出量为113.4μg·kg^(-1),1份检出氧氟沙星,检出量为8.23μg·kg^(-1),存在超标问题。建议后续加强对生猪养殖兽药使用监管力度,保障食品安全。In order to strengthen the food safety of pork,the veterinary drug residues in pork were determined by liquid chromatography-tandem mass spectrometry,with emphasis on the detection of enrofloxacin,ciprofloxacin,ofloxacin,ractopamine and other 6 common antibiotics.The existing detection methods were optimized,and the methodology evaluation and actual sample determination were carried out.The results show that the improved detection method is simple to operate and the sample recovery is higher.Among the 35 pork samples,1 part of enrof loxacin was detected,the detected amount was 113.4μg·kg^(-1),and 1 part of ofloxacin was detected,the detected amount was 8.23μg·kg^(-1),which had the problem of exceeding the standard.It is suggested to strengthen the subsequent supervision of the use of veterinary drugs in pig breeding to ensure food safety.

关 键 词：液相色谱串联质谱法 猪肉质检 兽药残留 

分 类 号：O657.63[理学—分析化学] TS251.51[理学—化学]