DcR3 suppresses the NF-κB pathway and the NLRP3 inflammasome activation in gouty inflammation  

作　　者：Yi Jiang Xin Tu Jianwei Guo Jianxiong Zheng Xia Liao Yixi He Yan Xie Quanbo Zhang Yufeng Qing 

机构地区：[1]Research Center of Hyperuricemia and Gout,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan 637000,China [2]Department of Rheumatology and Immunology,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan 637000,China [3]Department of Geriatrics,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan 637000,China

出　　处：《Chinese Medical Journal》2024年第21期2644-2646,共3页中华医学杂志(英文版)

摘　　要：To the Editor:Gouty arthritis,an autoinflammatory disease,exhibits a rapid onset of clinical symptoms but often resolve spontaneously within 7–10 days.In the acute gouty inflammatory responses,monosodium urate(MSU)crystal is recognized as damage-associated molecular patterns by Toll-like receptors(TLRs)on macrophage membranes.

关 键 词：NLRP3 DCR3 INFLAMMATION 

分 类 号：R73[医药卫生—肿瘤]