Chemical genetic approaches to dissect microbiota mechanisms in health and disease  

作　　者：Xinglin Yang 

机构地区：[1]不详

出　　处：《四川生理科学杂志》2025年第1期162-162,共1页

摘　　要：Advances in genomics,proteomics,and metabolomics have revealed associations between specific microbiota species in health and disease.However,the precise mechanism(s)of action for many microbiota species and molecules have not been fully elucidated,limiting the development of microbiota-based diagnostics and therapeutics.In this Review,we highlight innovative chemical and genetic approaches that are enabling the dissection of microbiota mechanisms and providing causation in health and disease.Although specific microbiota molecules and mechanisms have begun to emerge,new approaches are still needed to go beyond phenotypic associations and translate microbiota discoveries into actionable targets and therapeutic leads to prevent and treat diseases.

关 键 词：MECHANISMS TRANSLATE PRECISE 

分 类 号：R378[医药卫生—病原生物学]