MECHANISMS

作品数:1826被引量:7207H指数:33
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相关作者:杨运桂李琰朱海波张均田管华诗更多>>
相关机构:中国科学院中南大学温州医科大学东南大学更多>>
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Potential mechanisms of non-coding RNA regulation in Alzheimer's disease
《Neural Regeneration Research》2026年第1期265-280,共16页Yue Sun Xinping Pang Xudong Huang Dinglu Liu Jingyue Huang Pengtao Zheng Yanyu Wei Chaoyang Pang 
Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathological ch...
关键词:Alzheimer's disease biomarkers circular RNA long non-coding RNA microRNA ncRNA regulation NEURODEGENERATION non-coding RNA PATHOGENESIS therapeutic targets 
Syndecans in Alzheimer's disease:pathogenetic mechanisms and potential therapeutic targets
《Neural Regeneration Research》2025年第9期2594-2595,共2页Carmela Rita Balistreri Roberto Monastero 
supported by grants from the Next Generation EU-MUR D.M.737/2021-Project PSEBPEHRD-CUP B79J21038330001(to CRB)。
With increasing age,humans become more susceptible to the onset of neurodegenerative diseases(NDs),and among these,Alzheimer's disease(AD)is the most frequent(Nicoletti et al.,2023).NDs are primarily characterized by ...
关键词:ALZHEIMER CARDIOVASCULAR 
Mechanisms behind elevated serum levels of plasminogen activator inhibitor-1 in frontotemporal lobar degeneration
《Neural Regeneration Research》2025年第8期2317-2318,共2页Francesco Angelucci Jakub Hort 
funded by the project National Institute for Neurological Research(Programme EXCELES,ID Project No.LX22NPO5107);TEAMING:857560(EU);CZ.02.1.01/0.0/0.0/17_043/0009632(CZ)(to FA and JH)。
Frontotemporal lobar degeneration(FTLD)is a form of progressive dementia characterized by degeneration of the frontal and temporal lobes of the brain.This pathology involves a series of cognitive,behavioral,and neurol...
关键词:DEGENERATION ELEVATED PATHOLOGY 
Contribution of mechanical forces to structural synaptic plasticity:insights from 3D cellular motility mechanisms
《Neural Regeneration Research》2025年第7期1995-1996,共2页Rita O.Teodoro Mafalda Ribeiro Ramos Lara Carvalho 
supported by PTDC-01778/2022-NeuroDev3D,iNOVA4Health(UIDB/04462/2020 and UIDP/04462/2020);LS4FUTURE(LA/P/0087/2020)。
Cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no exception.Cell-intrinsic properties such as membrane lipid compositi...
关键词:PLASTICITY STRUCTURAL MECHANISMS 
Function,mechanism of action,metabolism,and commercial application of Lonicera japonica:a review
《Food Science and Human Wellness》2025年第3期783-805,共23页Xinli Yang Dan Yan 
supports from the National Natural Science Foundation of China(82130112,U24A20789);Beijing Hospitals Authority Ascent Plan(DFL20190702);Youth Beijing Scholar(2022-051)。
Lonicera japonica(honeysuckle)is a traditional Chinese medicinal food,in which the main active ingredients are phenolic acids,polysaccharides,flavonoids,and volatile oils.They have various biological activities,includ...
关键词:Lonicera japonica extract and functional components Health effects MECHANISMS Commercial application 
Salt reduction in cured meat products:a review on strategies and mechanisms
《Food Science and Human Wellness》2025年第3期864-879,共16页Qi Chen Jinxuan Cao Wenhai She Weidong Bai Xiaofang Zeng Hao Dong 
financially supported by Youth Talent Support Programme of Guangdong Provincial Association for Science and Technology(SKXRC202317);the Open Project of Beijing Laboratory of Food Quality and Safety/Key Laboratory of Alcoholic Beverages Quality and Safety of China Light Industry(FQS-202201);Characteristic Innovation Project of Guangdong Universities(2022KTSCX058);Special Projects in Key Field of Guangdong Universities(2022ZDZX4015,2022ZDZX4016);Guangdong Maoming Binhai New Area Marine Fishery Industrial Park Project(0835-220FA8102621);Guangdong Provincial Key Laboratory of Lingnan Specialty Food Science and Technology(2021B1212040013)。
Sodium chloride is one of the most widely used additives in meat curing.However,cured meat products contribute to a portion of the total sodium dietary intake.Consumers and researchers'concern about excessive sodium i...
关键词:Salt reduction Cured meat products Ultrasonic technology Salt substitutes High-pressure processing 
Key Mechanisms on Resource Optimization Allocation in Minority Game Based on Reinforcement Learning
《Tsinghua Science and Technology》2025年第2期721-731,共11页Changyan Di Tianyi Wang Qingguo Zhou Jinqiang Wang 
partially supported by the National Natural Science Foundation of China(Nos.U22A20261 and 61402210);the National Key R&D Program of China(No.2020YFC0832500);the Gansu Province Science and Technology Major Project-Industrial Project(No.22ZD6GA048);the Gansu Province Key Research and Development Plan-Industrial Project(No.22YF7GA004);the Fundamental Research Funds for the Central Universities(Nos.lzujbky-2022-kb12,lzujbky-2021-sp43,lzujbky-2020-sp02,lzujbky-2019-kb51,and lzujbky-2018-k12);the Science and Technology Plan of Qinghai Province(No.2020-GX-164);the Supercomputing Center of Lanzhou University,and the Gansu Provincial Science and Technology Major Special Innovation Consortium Project(No.21ZD3GA002)。
The emergence of coordinated and consistent macro behavior among self-interested individuals competing for limited resources represents a central inquiry in comprehending market mechanisms and collective behavior.Trad...
关键词:minority game optimization of resource allocation multi-agent system reinforcement learning 
Mechanisms and challenges of mesenchymal stem cells in the treatment of knee osteoarthritis
《World Journal of Stem Cells》2025年第4期1-5,共5页Jing-Shun Lu Chen-Yu Song Wen-Jing Cheng Kai-Yang Wang 
In this editorial,we comment on the recent article by Xiao et al,focusing on their investigation into whether the therapeutic efficacy of serum-free human umbilical cord mesenchymal stem cells(MSCs)differs from that o...
关键词:Mesenchymal stem cells Knee osteoarthritis INFLAMMATION EXOSOME Biological materials 
Gut microbiota's role in high-altitude cognitive impairment:the therapeutic potential of Clostridium sp.supplementation
《Science China(Life Sciences)》2025年第4期1132-1148,共17页Wei Zhou Yongqiang Zhou Shikun Zhang Bin Li Zhong Li Zhijie Bai Dezhi Sun Chaoji Huangfu Ningning Wang Tiantian Xia Congshu Huang Lina Guan Xi Yang Yangyi Hu Pengfei Zhang Pan Shen Rui Wang Zhexin Ni Yue Gao 
supported by the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202207,Y.G.);the Young Elite Scientists Sponsorship Program by CAST(2021-QNRC1-03,W.Z.)。
Prolonged exposure to high-altitude environments may increase the risk of cognitive decline in young migrants.Recent studies suggest that hypobaric hypoxia-induced alterations in gut microbial composition could partly...
关键词:HIGH-ALTITUDE cognition impairment microbial mechanisms Clostridium sp. L-VALINE 
Metabolomics, network pharmacology, and microbiome analyses uncover the mechanisms of the Chinese herbal formula for the improvement of meat quality in spent hens
《Journal of Animal Science and Biotechnology》2025年第2期948-964,共17页Zhihua Li Abul Kalam Azad Chengwen Meng Xiangfeng Kong Jue Gui Wenchao Lin Yadong Cui Wei Lan Qinghua He 
supported by the National Key Research and Development Project(2022YFC3400700);the City-School Cooperation Project of the Fuyang Science and Technology Special Fund undertaken by Fuyang Normal University(SXHZ2020007);the Basic Research Program of Shenzhen Municipal Government(JCYJ20200109114242138);the Special Commissioner for Rural Science and Technology of Guangdong Province(KTP20210345).
Background Meat originating from the spent hen is an important source of poultry meat production;however,multiple factors cause the decline in the meat quality of spent hens.Chinese herbs have been widely used as medi...
关键词:Cecal microbiota Chinese herbal formula Fatty acid Meat quality Network pharmacology Spent hens 
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