康复训练联合药物治疗对精神分裂症患者生活质量及社会功能的影响  

The effect of rehabilitation training combined with drug therapy on the quality of life and social function of patients with schizophrenia

作　　者：林婷婷 李志婷 王玉婷 LIN Ting-ting;LI Zhi-ting;WANG Yu-ting(Quanzhou Third Hospital,Quanzhou 362000,China)

机构地区：[1]泉州市第三医院,362000

出　　处：《中国现代药物应用》2025年第2期166-169,共4页Chinese Journal of Modern Drug Application

摘　　要：目的 分析康复训练联合药物治疗对精神分裂症患者生活质量及社会功能的影响。方法 遴选110例精神分裂症患者为研究对象,按照随机数字表法分为观察组与对照组,每组55例。对照组患者接受常规药物治疗,观察组患者在对照组基础上增加康复训练治疗。比较两组患者干预前后阳性与阴性症状量表(PANSS)评分,干预前后日常行为能力及社会能力,治疗安全性。结果 干预前,两组患者的PANSS中阳性症状量表、阴性症状量表、一般精神病理量表评分以及总分比较差异无统计学意义(P>0.05);干预后,观察组患者的PANSS中阳性症状量表、阴性症状量表、一般精神病理量表评分以及总分分别为(15.36±3.23)、(15.02±2.66)、(25.66±4.21)、(56.04±4.55)分,均显著低于对照组的(17.55±2.98)、(16.98±3.65)、(30.16±3.98)、(64.69±5.13)分(P<0.05)。干预前,两组患者的日常生活活动能力评定量表(ADL)评分及住院精神病患者社会功能评定量表(SSPI)评分比较差异无统计学意义(P>0.05);干预后,观察组患者的ADL评分(68.56±1.98)分、SSPI评分(35.56±4.65)分显著高于对照组的(61.56±2.81)、(30.65±4.09)分(P<0.05)。观察组患者治疗期间不良反应总发生率为23.64%(13/55),与对照组的27.27%(15/55)比较差异无统计学意义(P>0.05)。结论 对精神分裂症患者开展康复训练联合药物治疗的效果确切,能够改善患者临床症状,提高其生活能力和社会能力,且安全性与单纯药物干预相当。Objective To analyze the effect of rehabilitation training combined with drug therapy on the quality of life and social function of patients with schizophrenia.Methods 110 cases of schizophrenia patient were selected and divided into observation group and control group according to random number table method each with 55 patients.Patients in the control group received conventional drugs,and patients in the observation group received rehabilitation training on the basis of the control group.The positive and negative symptom scale(PANSS) score,daily behavior ability and social ability before and after the intervention,and treatment safety were compared between the two groups.Results Before the intervention,there was no significant difference in PANSS score for positive symptoms,negative symptoms,general psychopathology scale and total score between two group(P>0.05).After the intervention,the scores of PANSS positive symptom scale,negative symptom scale,genera psychopathology and total PANSS score in the observation group were (15.36±3.23),(15.02±2.66),(25.66±4.21)and (56.04±4.55) points,which were significantly lower than (17.55±2.98),(16.98±3.65),(30.16±3.98) and(64.69±5.13) points in the control group (P<0.05).Before the intervention,there was no significant difference in activities of daily living (ADL) score and social-skills for psychiatric inpatients (SSPI) score between the two groups (P>0.05).After the intervention,the observation group had ADL score of (68.56±1.98) points and SSP score of (35.56±4.65) points,which were significantly higher than (61.56±2.81) and (30.65±4.09) points in the control group (P<0.05).The total incidence of adverse reactions in the observation group was 23.64%(13/55)which had no significant difference compared with 27.27%(15/55) in the control group (P>0.05).Conclusion Rehabilitation training combined with drug therapy is effective for patients with schizophrenia,which can improve their clinical symptoms,living ability and social ability,and its safety is equivalent t

关 键 词：康复训练 药物治疗 精神分裂症 日常行为能力 社会能力 安全性 

分 类 号：R749.3[医药卫生—神经病学与精神病学]