Timing of biomarker changes preceding Alzheimer's disease:for diagnosis,treatment or prevention?  

作　　者：Meina Quan 

机构地区：[1]Innovation Center for Neurological Disorders and Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China [2]National Medical Center for Neurological Diseases and National Clinical Research Center for Geriatric Diseases,Beijing 100053,China [3]Center of Alzheimer’s Disease,Beijing Institute of Brain Disorders,Collaborative Innovation Center for Brain Disorders,Beijing 100053,China

出　　处：《Science China(Life Sciences)》2025年第2期575-577,共3页中国科学(生命科学英文版)

基　　金：supported by the Beijing Natural Science Foundation(L232136);the Youth Program of National Natural Science Foundation of China(82101503)。

摘　　要：The pathophysiological and behavioural features of Alzheimer’s disease(AD)have been extensively investigated in transgenic mouse models,including the temporal sequence of each pathophysiological change and behavioural abnormality,a summary of which was recently presented by our team in this Journal(Li et al.,2023).Nevertheless,studying such features and timings directly in human patients before symptoms occur is challenging.

关 键 词：PREVENTION ALZHEIMER DIAGNOSIS 

分 类 号：R749.16[医药卫生—神经病学与精神病学]