Pharmacological role of Herba Patriniae and Coix seed in colorectal cancer  

作　　者：Yu-Xin Zhang Hui Wan Guan-Yue Shan Jun-Ya Cheng Yi-Ying Liu Wen-Na Shi Hai-Jun Li 

机构地区：[1]Institute of Translational Medicine,The First Hospital of Jilin University,Changchun 130061,Jilin Province,China [2]Department of Bioengineering,Pharmacy School of Jilin University,Changchun 130061,Jilin Province,China [3]Institute of Liver Diseases,Institute of Translational Medicine,The First Hospital of Jilin University,Changchun 130061,Jilin Province,China

出　　处：《World Journal of Gastrointestinal Oncology》2025年第3期1-8,共8页世界胃肠肿瘤学杂志(英文)

基　　金：National Natural Science Foundation of China,No.81970529;The Natural Science Foundation of Jilin Province,No.20230508074RC and No.YDZJ202401218ZYTS.

摘　　要：Colorectal cancer(CRC)is the most prevalent cancer globally,and its traditional treatment modalities commonly encompass radiation therapy,chemotherapy,surgery and the administration of cytotoxic drugs.Currently,novel chemotherapy drugs that combine traditional Chinese medicine(TCM)with herbal extracts exhibit superior comprehensive benefits.Herein,we delved into an article authored by Wang et al,focusing specifically on the pharmacological effects of"Herba Patriniae and Coix seed(HC)"and their targeted mechanisms in combating CRC.From the perspective of TCM philosophy,damp-heat stagnation and toxicity are the cardinal pathogenic factors underlying CRC.HC,renowned for their abilities to antipyretic and enhance diuresis,have demonstrated promising efficacy in preliminary studies for the treatment of CRC.These findings offer potential insights in favor of fostering anti-cancer medications.

关 键 词：Colorectal cancer Herba Patriniae Coix seed ANTITUMOR Chinese medicine 

分 类 号：R73[医药卫生—肿瘤]