Endoscopic treatment outcome of oesophageal gastrointestinal stromal tumours  

作　　者：En-Pan Xu Zhi-Peng Qi Jia-Wei Zhang Bing Li Zhong Ren Ming-Yan Cai Shi-Lun Cai Zhen-Tao Lv Zhang-Han Chen Jing-Yi Liu Yun-Shi Zhong Ping-Hong Zhou Qiang Shi 

机构地区：[1]Endoscopy Center and Endoscopy Research Institute,Zhongshan Hospital,Fudan University,Shanghai 200032,China [2]Department of Gastroenterology,The First Affiliated Hospital of Ningbo University,Ningbo 315000,Zhejiang Province,China [3]Endoscopy Center,Shanghai Xuhui District Central Hospital,Shanghai 200030,China [4]Endoscopy Center and Endoscopy Research Institute,Shanghai Collaborative Innovation Center of Endoscopy,Zhongshan Hospital,Fudan University,Shanghai 200032,China

出　　处：《World Journal of Gastroenterology》2025年第10期62-70,共9页世界胃肠病学杂志(英文)

基　　金：Supported by National Natural Science Foundation of China,No.82002515,No.82273025 and No.82203460;China Postdoctoral Science Foundation,No.2022TQ0070 and No.2022M710759;Shanghai Municipal Commission of Science and Technology,No.22JC1403003,No.22XD1402200,No.19140901902 and No.22S31903800.

摘　　要：BACKGROUND There are few clinicopathologic characteristics and clinical results for oesophageal gastrointestinal stromal tumours(GISTs).Thus,the objective of this study was to identify the clinicopathologic characteristics and clinical results of oesophageal GISTs.AIM To investigate endoscopic treatment effective of oesophageal GISTs.METHODS It was retrospective research that collected 32 patients with oesophageal GISTs treated by endoscopic resection(ER)between January 2012 and January 2023 in two Hospital.Clinicopathologic,endoscopic records,and follow-up data were collected and analysed.RESULTS Thirty-one patients underwent en bloc resection and 24(75.0%)lesions underwent R0 resection.The size of GISTs was 2.12±1.88 cm.The overall complication rate was 25.0%,including hydrothorax and post-endoscopic submucosal dissection electrocoagulation syndrome.The mean mitotic index was 3.34±5.04(median,1.50;range,1.00-4.00).Eighteen(56.3%),6(18.8%),2(6.3%),and 6(18.8%)patients were identified as very low,low,intermediate,and high risk,respectively.Three patients developed recurrence after a median follow-up of 64.69±33.13 months.The 5-year overall survival rate was 100%,and the disease-free survival rate was 90.6%.CONCLUSION ER is safe and effective for patients with low-risk oesophageal GISTs.Early detection of oesophageal GISTs is essential to achieve a favourable prognosis.

关 键 词：Gastrointestinal stromal tumours OESOPHAGEAL Endoscopic resection Treatment outcome SURVIVAL 

分 类 号：R735.1[医药卫生—肿瘤]