核酸适配体电化学传感技术在食品安全中的应用  

Application of Aptamer Electrochemical Sensing Technology in Food Safety

作　　者：刘欢 汪恩婷[4] 陈玉皎 骆小方 刘方菁 丁龙 LIU Huan;WANG Enting;CHEN Yujiao;LUO Xiaofang;LIU Fangjing;DING Long(Chongqing Institute for Food and Drug Control,Chongqing 401121,China;Bioengineering College,Chongqing University,Chongqing 400044,China;Key Laboratory of Condiment Supervision Technology for State Market Regulation,Chongqing 401121,China;Chongqing Academy of Metrology and Quality Inspection,Chongqing 401121,China;Jinfeng Laboratory,Chongqing 401329,China;College of Food Science and Engineering,Northwest A&F University,Xianyang 712100,China)

机构地区：[1]重庆市食品药品检验检测研究院,重庆401121 [2]重庆大学生物工程学院,重庆400044 [3]国家市场监管重点实验室(调味品监管技术),重庆401121 [4]重庆市计量质量检测研究院,重庆401121 [5]金凤实验室,重庆401329 [6]西北农林科技大学食品科学与工程学院,陕西咸阳712100

出　　处：《食品安全导刊》2025年第6期173-176,共4页China Food Safety Magazine

基　　金：国家市场监督管理总局科技计划项目(2022MK109);重庆市自然科学基金项目资助(CSTB2023NSCQ-MSX0806);重庆市市场监督管理局科研资助项目(CQSJKJ2020027);重庆市科研机构绩效激励引导专项项目(cstc2020jxjl120007)。

摘　　要：本文论述核酸适配体、电化学传感技术等的原理和特点,并分析核酸适配体电化学传感技术在食品中塑化剂等污染物、赭曲霉毒素A等真菌毒素、卡那霉素和氯霉素等抗生素检测中的应用。通过探讨核酸适配体电化学传感技术的高特异性、高灵敏度和快速检测等优点,提出筛选稳定核酸适配体、优化电极材料、高通量筛查等发展方向,以期为核酸适配体电化学传感技术在食品安全中的进一步应用提供有益参考。This paper discusses the principle and characteristics of aptamer and electrochemical sensing technology,and analyzes the application of aptamer electrochemical sensing technology in food detection of plasticizers,mycotoxins such as oclatoxin A,kanamycin and chloramphenicol.By discussing the advantages of high specificity,high sensitivity and rapid detection of aptamer electrochemical sensing technology,the development direction of screening stable nucleic acid aptamer,optimizing electrode materials and high throughput screening is proposed,in order to provide useful reference for further application of nucleic acid aptamer electrochemical sensing technology in food safety.

关 键 词：核酸适配体 电化学传感器 食品安全 

分 类 号：O657.1[理学—分析化学] TS207.3[理学—化学]