益生菌联合果胶治疗老年习惯性便秘患者的临床疗效及对肠道功能的影响  

Clinical Efficacy and Effect of Probiotics Combined with Pectin on Intestinal Function in Elderly Patients with Habitual Constipation

作　　者：吴祖骄 张林芳 谭政 田名玉 施敏 肖杨静 WU Zujiao;ZHANG Linfang;TAN Zheng;TIAN Mingyu;SHI Min;XIAO Yangjing(Chengdu Eighth People's Hospital(Geriatric Hospital Affiliated to Chengdu Medical College),Chengdu,Sichuan,610083,China)

机构地区：[1]成都市第八人民医院(成都医学院附属老年医院),四川成都610083

出　　处：《中外医疗》2024年第36期1-4,23,共5页China & Foreign Medical Treatment

基　　金：2021年成都市医学科研课题项目(2021350)。

摘　　要：目的探讨老年习惯性便秘患者采用益生菌联合果胶治疗的临床疗效及对其肠道功能的影响。方法随机选取2021年6月—2023年6月于成都市第八人民医院接受治疗的80例老年习惯性便秘患者为研究对象,依据不同治疗方法分为对照组(n=40,益生菌治疗)和观察组(n=40,益生菌联合果胶治疗)。比较两组患者治疗效果,治疗前后肠道功能、排便症状评分、肠道菌群水平、胃肠生活质量评分。结果观察组治疗有效率为95.00%(38/40),高于对照组的77.50%(31/40),差异有统计学意义(χ^(2)=5.165,P=0.023)。观察组自主排便次数高于对照组,首次自主排便时间和首次肛门排气时间均短于对照组,差异均有统计学意义(P均<0.05)。治疗后,两组患者排便症状评分、肠道菌群水平均优于治疗前,胃肠生活质量评分高于治疗前,且观察组优于对照组,差异均有统计学意义(P均<0.05)。结论老年习惯性便秘采用益生菌联合果胶治疗效果显著,可改善排便症状评分、肠道菌群水平,提升肠道功能和整体生活质量。Objective To investigate the clinical efficacy and effect of probiotics combined with pectin on intestinal function in elderly patients with habitual constipation.Methods 80 elderly patients with habitual constipation who received treatment in Chengdu Eighth People's Hospital from June 2021 to June 2023 were randomly selected as the study objects,and were divided into control group(n=40,probiotic treatment)and observation group(n=40,probiotic combined with pectin treatment)according to different treatment methods.The therapeutic effect,intestinal function,bowel symptom score,intestinal flora level and gastrointestinal quality of life score before and after treatment were compared between the two groups.Results The effective rate of the observation group was 95.00%(38/40),which was higher than that of the control group 77.50%(31/40),the difference was statistically significant(χ^(2)=5.165,P=0.023).The frequency of spontaneous defecation in the observation group was higher than that in the control group,and the time of first spontaneous defecation and first anal exhaust were shorter than those in the control group,the differences were statistically significant(all P<0.05).After treatment,defecation symptom score and intestinal flora level in the two groups were better than before treatment,gastrointestinal quality of life score was higher than before treatment,and observation group were better than control group,the differences were statistically significant(all P<0.05).Conclusion The effect of probiotics combined with pectin in the treatment of habitual constipation in the elderly is significant,which can improve the score of defecation symptoms,the level of intestinal flora,and improve intestinal function and overall quality of life.

关 键 词：益生菌 果胶 老年习惯性便秘 临床疗效 肠道功能 

分 类 号：R574[医药卫生—消化系统]