不同市售食品中黄曲霉毒素的污染趋势及暴露风险评估  

Contamination trend and exposure risk assessment of aflatoxins in different commercially available foods

作　　者：商蕾[1] 吕俊庆 齐志彩[1] 王丽英[2] 任贝贝[2] 王育灿[1] SHANG Lei;LYU Junqing;QI Zhicai;WANG Liying;REN Beibei;WANG Yucan(Physical and Chemical Laboratory,Xingtai Center for Disease Control and Prevention,Xingtai,Hebei 054000,China;Physical and Chemical Testing Institute,Hebei Province Center for Disease Control and Prevention,Shijiazhuang,Hebei 050021,China)

机构地区：[1]邢台市疾病预防控制中心理化检验科,河北邢台054000 [2]河北省疾病预防控制中心理化检验所,河北石家庄050021

出　　处：《职业与健康》2024年第24期3342-3346,共5页Occupation and Health

基　　金：河北省医学科学研究课题(20210101)。

摘　　要：目的了解河北省不同食品种类中黄曲霉毒素的污染状况,对9种市售食品中的黄曲霉毒素进行定量测定,评估其暴露水平及潜在的健康风险,为相关部门的预警提供数据支撑。方法2021—2023年,采集河北省市售食品样品共计404份,样品用乙腈-水(84+16)提取,免疫亲和柱进行净化处理,液相色谱串联三重四级杆质谱仪进行检测,同位素内标法进行定量,并根据黄曲霉毒素B1含量的数据、营养监测消费量的数据对黄曲霉毒素B1暴露水平进行评估。结果食品中黄曲霉毒素B1的检出率最高,为12.13%;在各类食品中,花生酱中黄曲霉毒素B1检出率最高,检出平均值为93.3μg/kg;花生酱的暴露风险较高,暴露边界值(the margin of exposure,MOE)为72.99。结论河北省不同市售食品中黄曲霉毒素B1的污染应高度关注,尤其注意花生及花生酱对居民的暴露风险。Objective To understand the contamination status of aflatoxins in different food in Hebei Province,quantitatively determine the aflatoxins in 9 commercially available foods,evaluate their exposure levels and potential health risks,and provide data support for relevant departments'early warning.Methods From 2021 to 2023,a total of 404 samples of food sold in Hebei Province were collected.The samples were extracted with acetonitrile-water(84+16),purified with an immunoaffinity column,detected by liquid chromatography-tandem triple quadrupole mass spectrometry,quantified with isotope internal standard method.Based on the aflatoxin B1 content data and nutritional monitoring consumption data,the exposure level of aflatoxin B1 was assessed.Results The detection rate of aflatoxin B1 in food was the highest,at 12.13%.Among various types of food,peanut butter had the highest detection rate of aflatoxin B1,with an average detection value of 93.3μg/kg.The exposure risk of peanut butter was relatively high,with the margin of exposure(MOE)of 72.99.Conclusion The contamination of aflatoxin B1 in food sold in different markets in Hebei Province should be highly concerned,especially the exposure risk of peanuts and peanut butter to residents.

关 键 词：黄曲霉毒素 食品污染 暴露风险评估 

分 类 号：R155.3[医药卫生—营养与食品卫生学]