Post-fast refeeding:rise of intestinal stemness and mutageninduced cancer risk through polyamine metabolism  

作　　者：Sarah Brunner Klaus-Peter Janssen Josef Ecker 

机构地区：[1]Institute of Clinical Chemistry and Laboratory Medicine,Functional Lipidomics and Metabolism Research,University Hospital Regensburg,Regensburg,Germany [2]Technical University of Munich,School of Medicine and Health,Dept.of Surgery,81675 Munich,Germany

出　　处：《Signal Transduction and Targeted Therapy》2024年第12期5357-5358,共2页信号转导与靶向治疗(英文)

基　　金：support from the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)project no 395357507-SFB 1371.

摘　　要：An increased intestinal stem cell activity following post fastrefeeding is beneficial for regeneration,but too much could increase the risk for cancer in mice,as reported in a recent study by Imada and colleagues published in Nature.1 In consequence,fast-refeeding cycles should be thoroughly planned,when dietary strategies are considered for regeneration to minimize cancer risks.

关 键 词：metabolism cancer DIETARY 

分 类 号：R73[医药卫生—肿瘤]