Catalyst-Free, Radical Tri- and Difluoromethylation of Isocyanides and N-Arylacrylamides Using Rotating Magnetic Field and Metal Rods  

作　　者：Xuliang Han Haodong Liu Xiaomei Feng Fuchao Jia Zengdian Zhao Xinjin Li 

机构地区：[1]School of Chemistry and Chemical Engineering,Shandong University of Technology,Zibo,Shandong,255000 China [2]School of Physics and Optoelelctronic Engineering,Shandong University of Technology,Zibo,Shandong,255000 China

出　　处：《Chinese Journal of Chemistry》2025年第2期155-160,共6页中国化学(英文版)

基　　金：support by the National Natural Science Foundation of China(22101157)is gratefully acknowledged;We are very grateful to Prof.Xiao Shen(Wuhan University,China)for helpful discussion.

摘　　要：The pursuit of sustainable and environmentally benign synthetic methods continues to challenge organic chemists. Herein, we introduce a magnetoredox system for tri- and difluoromethylation of isocyanides and N-arylacrylamides using a rotating magnetic field and steel rods. This magnetoredox approach enables facile synthesis of functionalized phenanthridines and oxindoles without the need for catalysts and additives under mild conditions. Such a system potentially represents an attractive strategy for selective formation of bonds through multifaceted regulation of magnetic intensity, rotating frequency, and rod size.

关 键 词：TRIFLUOROMETHYLATION DIFLUOROMETHYLATION Radical Single-electron transfer CATALYST-FREE Magnetic field Electromagnetic induction ISOCYANIDES 

分 类 号：O62[理学—有机化学]