CD4 T cell contact drives macrophage cell cycle G0-G1 transition  

作  者:Petra Mlcochova Na Zhao Omar Shabana Roman Fischer Ravindra K.Gupta 

机构地区:[1]Cambridge Institute of Therapeutic Immunology&Infectious Disease(CITIID),University of Cambridge,Cambridge,UK [2]University of Oxford,Oxford,UK

出  处:《Signal Transduction and Targeted Therapy》2025年第1期21-23,共3页信号转导与靶向治疗(英文)

基  金:supported by the NIHR Cambridge Biomedical Research Centre(NIHR203312).

摘  要:Dear Editor Macrophages are cells implicated in a diverse array of functions such as defence against pathogens,tissue repair/homoeostasis,and anti-cancer activity.1,2 Macrophages are also targets of virus infection,and SAMHD1 is known to restrict lentiviruses through depletion of intracellular dNTP and inhibition of reverse transcription.

关 键 词:STASIS MACROPHAGE infection 

分 类 号:R73[医药卫生—肿瘤]

 

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