纳米酶标记免疫分析技术在食品安全检测应用中的研究进展  

Research progress on immunoassay technology based on nanoenzyme labeling in detection of food safety

作　　者：刘紫洋 胡高爽 郝建雄[1] 王晨宇 史莹莹 俞清秀 LIU Ziyang;HU Gaoshuang;HAO Jianxiong;WANG Chenyu;SHI Yingying;YU Qingxiu(College of Food and Biology,Hebei University of Science and Technology,Shijiazhuang,Hebei 050000,China)

机构地区：[1]河北科技大学食品与生物学院,河北石家庄050000

出　　处：《食品与机械》2025年第1期234-242,共9页Food and Machinery

基　　金：河北省教育厅科研项目(编号:BJK2024191);河北省现代农业产业技术体系建设专项基金(编号:HBCT2024270206)。

摘　　要：食品安全问题现已成为全社会共同关注的热点话题,而高效、灵敏的检测技术是保障食品安全的重要工具。免疫分析法是生化靶点高灵敏度检测的金标准,为食品污染物的检测提供了良好的平台,近年来逐渐被应用于各类食品安全检测。纳米酶作为一种天然酶的模拟物,具有稳定性好、灵敏度高等优势,符合日益降低的检测限形势下对快检方法的要求。文章综述了基于纳米酶标记的免疫分析技术的检测原理和优势所在,对该技术在不同食品安全检测领域包括农兽药残留、重金属残留、真菌毒素、食源性致病菌、其他有害物检测等的应用实例进行了阐述,同时对纳米酶未来的发展趋势进行了讨论。Food safety has become a hot topic of widespread concern across society,and efficient,sensitive detection technologies are essential tools for ensuring food safety.Immunoassay is the gold standard for high-sensitivity detection of biochemical targets,providing an excellent platform for the detection of food contaminants.In recent years,it has gradually been applied to various food safety detection methods.Nanoenzymes,as synthetic analogs of natural enzymes,offer advantages such as good stability and high sensitivity,meeting the demands of rapid detection methods under increasingly stringent detection limits.This article reviews the detection principles and advantages of immunoassay technology based on nanoenzyme labeling,discussing its applications in different areas of food safety detection,including agricultural and veterinary drug residues,heavy metal residues,mycotoxins,foodborne pathogenic bacteria,and other harmful substances.It also addresses the future development trends of nanoenzymes.

关 键 词：纳米酶 免疫分析技术 食品安全 检测 

分 类 号：TS207.3[轻工技术与工程—食品科学] TS201.6[轻工技术与工程—食品科学与工程] O657[理学—分析化学]