A novel nested gene Aff3ir participates in vascular remodeling by enhancing endothelial cell differentiation in mice  

作　　者：Yue Zhao Mazdak Ehteramyan Yi Li Xuefeng Bai Lei Huangg Yingtang Gao Angshumonik Angbohangg Xiaoping Yang Steven Lynham Andriana Margariti Ajay M.Shah Yaling Tao Ting Cai Tong Li Min Zhang Lingfang Zeng 

机构地区：[1]Department of Heart Center,Nankai University Affiliated Third Center Hospital,Tianjin 300170,China [2]School of Cardiovascular and Metabolic Medicine and Sciences,King's College London British Heart Foundation Centre of Excellence,Faculty of Life Science and Medicine,King's College London,London SE59NU,United Kingdom [3]School of Medicine,Nankai University,Tianjin 300071,China [4]Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases,Nankai University Affiliated Third Center Hospital,Tianjin 300170,China [5]Tianjin Institute of Hepatobiliary Disease,Nankai University Affiliated Third Centre Hospital,Tianjin 300170,China [6]Wellcome-Wolfson Institute for Experimental Medicine,Queen's University Belfast,Belfast BT97BL,United Kingdom [7]Ningbo Institute of Life and Health Industry,University of Chinese Academy of Sciences,Ningbo,Zhejiang 315010,China

出　　处：《Genes & Diseases》2025年第2期106-109,共4页基因与疾病(英文)

基　　金：supported by a British Heart Foundation PhD studentshipFS-15-74-31669 (to L.Z.);projectgrantPG/22/11055 (to M.Z.);partially supported by the China Scholarship Council。

摘　　要：Gene overlap serves as a common strategy employed by bacteria and viruses to expand their genomic capacity.Over the past two decades,advances in omics studies have unveiled a prevalence of overlapped genes in eukaryotes,including mammals.However,few are reported to participate in the regulation of the cardiovascular system.

关 键 词：CARDIOVASCULAR REMODELING PREVALENCE 

分 类 号：R73[医药卫生—肿瘤]