桔梗皂苷的研究进展  

Research progress on Platycodon grandiflorum saponins

作　　者：郑亚文 杨潇 严一字[1] 崔泰花[1] 金清[1] ZHENG Yawen;YANG Xiao;YAN Yizi;CUI Taihua;JIN Qing(College of Agriculture,Yanbian University,Yanji,Jilin 133002,China)

机构地区：[1]延边大学农学院,吉林延吉133002

出　　处：《食品与机械》2025年第2期206-215,共10页Food and Machinery

基　　金：吉林省科技厅科技攻关计划重点科技攻关项目(编号:20220204048YY,20160204003YY);延边大学科技发展计划项目(编号:ydkj202304);延边大学校企合作项目(编号:ydkj20230035)。

摘　　要：桔梗含有皂苷、黄酮、苯酚、多糖等多种类型的化学成分,其中皂苷类化合物是桔梗的主要活性物质。目前国内外研究人员对桔梗皂苷功效机制及药理活性做了大量研究,结果发现桔梗皂苷具有良好的止咳平喘、护肝、抗肿瘤、抗氧化、抗炎镇痛等保健功能。文章对桔梗皂苷的化学成分与结构、提取纯化、功效作用进行了综述,阐述了桔梗皂苷的研究现状,并对桔梗未来的研究方向进行了展望。Platycodon grandiflorum contains various chemical components,including saponins,flavonoids,phenolic compounds,and polysaccharides,among which saponins are the main active substances.Extensive research has been conducted both in China and abroad on the efficacy mechanisms and pharmacological activities of P.grandiflorum saponins.These studies have found that P.grandiflorum saponins exhibit significant health benefits,including cough suppression,asthma relief,liver protection,anti-tumor effects,antioxidant properties,and anti-inflammatory and analgesic actions.This article provides a review of the chemical composition and structure,extraction and purification methods,as well as the efficacy of P.grandiflorum saponins.It also discusses the current state of research on P.grandiflorum saponins and offers prospects for future research directions.

关 键 词：桔梗 皂苷 化学成分 提取纯化 保健功能 研究进展 

分 类 号：R28[医药卫生—中药学]