睡眠质量与青少年干眼症状的关联  

Association between sleep quality and dry eye symptoms among adolescents

作　　者：谢佳煜 李丹琳 董兴璇 开佳妍 李娟 吴一波 潘臣炜[1] XIE Jiayu;LI Danlin;DONG Xingxuan;KAI Jiayan;LI Juan;WU Yibo;PAN Chenwei(School of Public Health,Suzhou Medical College of Soochow University,Suzhou(215123),Jiangsu Province,China)

机构地区：[1]苏州大学苏州医学院公共卫生学院,江苏215123 [2]西安市人民医院(西安市第四医院)眼科 [3]北京大学公共卫生学院

出　　处：《中国学校卫生》2025年第2期276-279,284,共5页Chinese Journal of School Health

基　　金：南开大学眼科学研究院开放基金项目(NKYKD202206)。

摘　　要：目的探索青少年睡眠质量和干眼症状之间的关联,为降低青少年干眼症状患病率提供参考。方法研究对象为来自中国居民心理与行为调查(PBICR)的12~24岁青少年,于2022年6月20日—8月31日,采用分层随机与配额抽样相结合的方法在中国内地范围选取6456名青少年,并对其使用眼表疾病指数(OSDI)和简版匹兹堡睡眠质量指数(B-PSQI)评估干眼症状和睡眠质量。应用多元Logistic回归模型探索睡眠质量与青少年干眼症状之间的关系,利用交互项探讨性别对关联的影响。结果共有2815名青少年报告存在干眼症状,报告率为43.6%。Logistic回归分析结果显示,睡眠质量不良的青少年干眼症状加重的风险增加,与睡眠质量良好组相比,睡眠质量不良组轻度、中度和重度干眼症状的OR值(95%CI)分别为1.39(1.16~1.67),1.52(1.28~1.81),2.35(2.02~2.72)(P值均<0.05)。睡眠质量和性别对青少年干眼症状的交互作用有统计学意义(P<0.01)。结论睡眠质量与青少年干眼症状之间存在关联,睡眠质量不良者干眼症状加重的风险更高,其影响在男生中更大。Objective To explore the association between sleep quality and dry eye symptoms in adolescents,so as to provide the evidence for reducing the prevalence of dry eye symptoms.Methods The study population was adolescents aged 12-24 years from the Psychology and Behavior Investigation of Chinese Residents(PBICR)survey,which was conducted from 20 June to 31 August 2022.A stratified random sampling and quota sampling method was used to select 6456 adolescents within China's Mainland.The Ocular Surface Disease Index(OSDI)and Brief version of the Pittsburgh Sleep Quality Index(B-PSQI)were used to assess dry eye symptoms and sleep quality.Multiple Logistic regression model was used to explore the relationship between sleep quality and dry eye symptoms in adolescents.The influence of gender on the association was explored by using interaction terms.Results A total of 2815 adolescents reported having dry eye symptoms,with a prevalence of 43.6%.Logistic regression analysis results showed an increased risk of exacerbation of dry eye symptoms in adolescents with poor sleep quality.The OR(95%CI)for mild,moderate,and severe dry eye symptoms groups were 1.39(1.16-1.67),1.52(1.28-1.81),and 2.35(2.02-2.72),respectively,compared with the ocularly normal group(P<0.05).There was a significant interaction between sleep quality and gender on dry eye symptoms in adolescents(P<0.01).Conclusions Sleep quality is associated with dry eye symptoms in adolescents,and those with poor sleep quality have a higher risk of dry eye symptoms.The effect of sleep quality on dry eye symptoms is greater in boys.

关 键 词：睡眠 干眼病 回归分析 青少年 

分 类 号：B844.2[哲学宗教—发展与教育心理学] R591.412[哲学宗教—心理学] Q428[医药卫生—内科学]