青少年抑郁患者非自杀性自伤相关因素分析  

Correlative factors of non-suicidal self-injury in adolescents with depression

作　　者：和杰 吴夏倩 詹妍妮 杜雪 陈平周 李慧[1,2] HE Jie;WU Xiaqian;ZHAN Yanni;DU Xue;CHEN Pingzhou;LI Hui(Shantou University Mental Health Center,Shantou 515065,China;Shantou University Medical College-University of Manitoba Medical School Joint Laboratory of Biological Psychiatry,Shantou 515065,China)

机构地区：[1]汕头大学精神卫生中心,广东汕头515065 [2]汕头大学医学院—曼尼托巴大学医学院生物精神病学联合实验室,广东汕头515065

出　　处：《汕头大学医学院学报》2025年第1期10-14,21,共6页Journal of Shantou University Medical College

基　　金：广东省科技专项资金(210728166901959)。

摘　　要：目的:探讨青少年抑郁患者中非自杀性自伤(non-suicidal self-injury,NSSI)的相关因素,以便早期识别NSSI风险,预防其发生。方法:本研究为病例对照研究,回顾性纳入2021年9月—2023年10月期间在汕头大学精神卫生中心就诊的98例青少年患者。依据NSSI的诊断标准,将患者分为两组:抑郁伴NSSI组(n=66)和抑郁不伴NSSI组(n=32)。采用汉密尔顿抑郁量表、汉密尔顿焦虑量表、简明精神病评定量表-阳性症状量表、贝克绝望量表、Barratt冲动性量表、儿童期创伤量表、NSSI行为评定问卷评估患者的临床症状。采用多因素logistic回归筛选青少年抑郁患者NSSI行为的相关因素。结果:抑郁伴NSSI组患者的汉密尔顿抑郁量表、汉密尔顿焦虑量表、简明精神病评定量表-阳性症状量表、贝克绝望量表、Barratt冲动性量表(非计划性冲动、行为冲动、认知冲动)、儿童期创伤量表(情感忽视、情感虐待、躯体忽视和躯体虐待)得分高于抑郁不伴NSSI组(均P<0.05)。多因素logistics回归结果显示Barratt冲动性量表的行为冲动得分(OR=0.85,95%CI:0.74~0.98)、儿童期创伤量表的情感忽视得分(OR=0.80,95%CI:0.64~0.99)和情感虐待得分(OR=0.74,95%CI:0.56~0.99)是青少年抑郁患者NSSI行为的相关因素。结论:行为冲动、情感忽视和情感虐待可能会增加青少年抑郁患者的NSSI风险。Objective:To investigate the associated factors of non-suicidal self-injury(NSSI)in adolescents with depression,so as to identify the risk of NSSI early and prevent its occurrence.Methods:This study was a case-control study,and 98 adolescent patients who visited Shantou University Mental Health Center from September 2021 to October 2023 were retrospectively included.According to the diagnostic criteria of NSSI,the patients were divided into two groups:depression with NSSI group(n=66)and depression without NSSI group(n=32).The Hamilton Depression Scale,Hamilton Anxiety Scale,Brief Psychiatric Rating Scale-Positive Symptom Scale,Beck Hopelessness Scale,Barratt Impulsiveness Scale,Childhood Trauma Questionnaire and NSSI Behavior Rating Questionnaire were used to evaluate the clinical symptoms of the patients.Multivariate logistic regression was used to screen the related factors of NSSI behavior in adolescent patients with depression.Results:The scores of Hamilton Depression Scale,Hamilton Anxiety Scale,Brief Psychiatric Rating Scale-Positive Symptom Scale,Beck Hopelessness Scale,Barratt Impulsiveness Scale(unplanned impulsivity,behavioral impulsivity,cognitive impulsivity),and Child Trauma Questionnaire(emotional neglect,emotional abuse,physical neglect,and physical abuse)in the depression with NSSI group were higher than those in the depression without NSSI group(all P<0.05).Multivariate logistics regression results showed that the Barratt Impulsiveness Scale behavioral impulsivity score(OR=0.85,95%CI:0.74-0.98),Child Trauma Questionnaire emotional neglect score(OR=0.80,95%CI:0.64-0.99),and emotional abuse score(OR=0.74,95%CI:0.56-0.99)were associated with NSSI behavior in adolescents with depression.Conclusion:Behavioral impulsivity,emotional neglect,and emotional abuse may increase the risk of NSSI in adolescents with depression.

关 键 词：非自杀性自伤 抑郁 青少年 冲动性 情感忽视 情感虐待 

分 类 号：R749[医药卫生—神经病学与精神病学]