山楂水提物制备泡腾片工艺优化及抗氧化活性研究  

Study on process optimization and antioxidant activity of effervescent tablets prepared by hawthorn aqueous extract

作　　者：李晓 孔欣欣[1] 王成 郭楠楠[1] 潘道东[2] LI Xiao;KONG Xinxin;WANG Cheng;GUO Nannan;PAN Daodong(College of Food Science and Engineering,Zhengzhou University of Science and Technology,Zhengzhou 450006,China;College of Food and Pharmacy,Ningbo University,Ningbo 315800,China)

机构地区：[1]郑州科技学院食品科学与工程学院,郑州450006 [2]宁波大学食品与药学学院,浙江宁波315800

出　　处：《包装与食品机械》2025年第1期106-112,共7页Packaging and Food Machinery

基　　金：河南省大学生创新训练计划项目(S202112746035);2024年度河南省高等教育教学改革研究与实践重点项目(2024SJGLX0219)。

摘　　要：为充分发挥山楂活性成分的潜在功效,探索其在新型制剂中的应用价值,选用山楂水提物、甜菊糖苷、麦芽糊精、微晶纤维素进行单因素试验,通过响应面优化法确定山楂水提物泡腾片的最佳工艺条件,对最优工艺下的泡腾片进行品质检测和抗氧化能力分析。结果表明,最佳工艺条件为山楂水提物添加量5.8 g,甜菊糖苷添加量3.0 g,麦芽糊精添加量1.6 g,微晶纤维素添加量0.4 g;在此条件下制备得到的泡腾片pH值为3.97,发泡量为12 mL/g,崩解时限为174 s;当山楂水提物泡腾片溶液的浓度达到10 g/L时,DPPH自由基、ABTS阳离子自由基和羟自由基的清除率分别达到71.68%,74.03%,67.33%。研究为开发具有抗氧化功能的新型泡腾片产品提供科学依据。To fully exploit the potential efficacy of active components in hawthorn and explore their application value in novel formulations,single-factor experiments were conducted using hawthorn aqueous extract,stevioside,maltodextrin,and microcrystalline cellulose.The optimal process conditions for hawthorn aqueous extract effervescent tablets were determined through response surface methodology(RSM).Quality testing and antioxidant capacity analysis were performed on the tablets prepared under the optimized conditions.Results showed that the optimal parameters were:hawthorn aqueous extract dosage of 5.8 g,stevioside dosage of 3.0 g,maltodextrin dosage of 1.6 g,and microcrystalline cellulose dosage of 0.4 g.Under these conditions,the effervescent tablets exhibited a pH of 3.97,foaming volume of 12 mL/g,and disintegration time of 174 s.When the concentration of the effervescent tablet solution reached 10 g/L,the scavenging rates against DPPH radicals,ABTS cation radicals,and hydroxyl radicals reached 71.68%,74.03%,and 67.33%,respectively.This study provides a scientific basis for developing novel antioxidant effervescent tablet products.

关 键 词：山楂水提物 泡腾片 工艺优化 抗氧化 

分 类 号：TS278[轻工技术与工程—农产品加工及贮藏工程]