不同强度运动干预对原发性高血压病人血压、心肺耐力的影响  

Effects of different intensity exercise intervention on blood pressure and cardiopulmonary endurance in patients with essential hypertension

作　　者：刘双虎 宋浩明[5] 李焕[6] 马肖 关顺凯 陈嘉 LIU Shuanghu;SONG Haoming;LI Huan;MA Xiao;GUAN Shunkai;CHEN Jia(School of Medicine,Tongji University,Shanghai 200082,China;Department of Cardioelectrophysiology,Cangzhou People's Hospital,Cangzhou,Hebei 061000,China;Department of Medical Laboratory,Cangzhou People's Hospital,Cangzhou,Hebei 061000,China;Department of Cardiology,Cangzhou People's Hospital,Cangzhou,Hebei 061000,China;Department of Cardiovascular Medicine,Tongji Hospital,Tongji University,Shanghai 200000,China;Department of Nursing,Cangzhou Medical College,Cangzhou,Hebei 061000,China)

机构地区：[1]同济大学医学院,上海200082 [2]沧州市人民医院心脏电生理科,河北沧州061000 [3]沧州市人民医院医学检验科,河北沧州061000 [4]沧州市人民医院心血管内科,河北沧州061000 [5]同济大学附属同济医院心血管内科,上海200000 [6]沧州医学高等专科学校护理教研室,河北沧州061000

出　　处：《安徽医药》2025年第5期1006-1011,共6页Anhui Medical and Pharmaceutical Journal

基　　金：河北省医学科学研究课题(20220318)。

摘　　要：目的探讨不同强度运动干预对原发性高血压病人血压、心肺耐力的影响。方法选取2021年8―12月在沧州市人民医院就诊的原发性高血压病人48例,其中32例病人进行常规药物合并运动干预治疗为研究组,16例病人进行常规药物治疗为对照组。研究组按照运动干预方式分为低强度持续有氧运动组(A组)和高强度间歇运动组(B组)两个亚组,每组16例病人。干预持续8周,分别在干预前、干预后检测两组病人血压、心肺耐力、血脂水平及心理状态的变化情况。结果干预后对照组、A组、B组24 h平均收缩压[(145.63±5.32)mmHg、(140.25±4.77)mmHg、(135.19±4.92)mmHg比(149.19±5.71)mmHg、(149.31±5.02)mmHg、(150.00±5.82)mmHg]、24 h平均舒张压[(86.81±8.76)mmHg、(84.31±9.00)mmHg、(79.88±9.58)mmHg比(88.56±9.28)mmHg、(88.13±10.22)mmHg、(87.50±13.60)mmHg]、白天平均收缩压、收缩压负荷、舒张压负荷均低于干预前(P<0.05),B组病人干预后24 h平均收缩压、白天平均收缩压、晨峰血压改善优于A组(P<0.05);与干预前比较,干预后A、B两组病人无氧阈公斤摄氧量、峰值公斤摄氧量明显升高(P<0.05),A、B两组三酰甘油、总胆固醇、低密度脂蛋白、葡萄糖、糖化血红蛋白水平明显降低(P<0.05),改善程度均优于对照组;相较于对照组,两种运动方式干预后病人抑郁症状群和广泛性焦虑量表评分均明显降低(P<0.05);干预过程中,病人均未发生恶性心律失常或明显心肌缺血症状,运动过程中无收缩压进行性下降及异常升高。结论高强度间歇运动可帮助原发性高血压病人控制血压,提高心肺耐力,降低血脂水平,且干预过程无不良反应事件发生,应用安全性理想。Objective To investigate the impacts of exercise intervention with different intensity on blood pressure,and cardiopulmonary endurance in patients with primary hypertension.Methods A total of 48 patients with essential hypertension were included in the Cangzhou People's Hospital from August to December 2021.Among them,32 patients were treated with conventional drugs combined with exercise intervention as the study group,and 16 patients were treated with conventional drugs as the control group.According to the exercise intervention,they were assigned into two subgroups:low-intensity continuous aerobic exercise group(group A)and high-intensity intermittent exercise group(group B),with 16 patients in each group.The intervention lasted for 8 weeks.The changes of blood pressure,cardiopulmonary endurance,blood lipid level and psychological state of the two groups were detected before and after intervention.Results After intervention,the 24 h mean systolic blood pressure[(145.63±5.32)mmHg,(140.25±4.77)mmHg,(135.19±4.92)mmHg vs.(149.19±5.71)mmHg,(149.31±5.02)mmHg,(150.00±5.82)mmHg],24 h mean diastolic blood pressure[(86.81±8.76)mmHg,(84.31±9.00)mmHg,(79.88±9.58)mmHg vs.(88.56±9.28)mmHg,(88.13±10.22)mmHg,(87.50±13.60)mmHg],daytime mean systolic blood pressure,systolic blood pressure load and diastolic blood pressure load of the three groups were lower than those before intervention(P<0.05).The improvement of 24 h mean systolic blood pressure,daytime mean systolic blood pressure and morning peak blood pressure in group B were better than those in group A(P<0.05);after intervention,the anaerobic threshold kg oxygen uptake and peak kg oxygen uptake of patients in groups A and B increased significantly compared with before intervention(P<0.05),and the levels of triglyceride,total cholesterol,low density lipoprotein,glucose and glycosylated hemoglobin in groups A and B decreased significantly(P<0.05),and the improvement degree was better than that of control group;compared with the control group,the scores of depre

关 键 词：高血压 运动干预 血压 心肺耐力 血脂 心理 

分 类 号：R544.1[医药卫生—心血管疾病]