药物治疗与血管内支架治疗无症状性颈内动脉狭窄的临床疗效分析  

Analysis of the Clinical Effi cacy of Pharmacological Treatment and Endovascular Stenting in Asymptomatic Internal Carotid Artery Stenosis

作　　者：张斌 魏洪涛[2] 孟庆龙[2] 胡雄[1,2] Zhang Bin;Wei Hongtao;Meng Qinglong;Hu Xiong(Medical College,Northwest Minzu University,Lanzhou,Gansu 730000;Affi liated Hospital of Northwest Minzu University(The Second People’s Hospital of Gansu Province),Lanzhou,Gansu 730000)

机构地区：[1]西北民族大学医学院,甘肃兰州730000 [2]西北民族大学附属医院(甘肃省第二人民医院),甘肃兰州730000

出　　处：《科技与健康》2025年第4期9-12,共4页Technology and Health

摘　　要：探讨药物治疗与血管内支架治疗无症状性颈内动脉狭窄的临床效果。选取2023年1月—2024年6月在西北民族大学附属医院治疗的72例无症状性颈内动脉狭窄患者为研究对象,随机将其分为对照组和观察组,每组各36例。对照组使用药物治疗,观察组使用血管内支架治疗。结果显示,观察组血管再通率优于对照组(P<0.05);观察组治疗1个月的rCBF、rCBV水平高于对照组,MTT、PSV、PI水平低于对照组(P<0.05)。研究发现,与药物治疗相比,血管内支架治疗无症状性颈内动脉狭窄的临床疗效更佳,能有效增加脑血流量,改善脑血流动力学,且对认知功能的影响小。This study aims to explore the clinical effects of pharmacological treatment and endovascular stenting in the treatment of asymptomatic internal carotid artery stenosis.A total of 72 patients with asymptomatic internal carotid artery stenosis treated in the Affiliated Hospital of Northwest Minzu University from January 2023 to June 2024 were selected as the research subjects and randomly divided into a control group and an observation group,with 36 cases in each group.The control group received pharmacological treatment,while the observation group received endovascular stenting treatment.The results showed that the vascular recanalization rate of the observation group was better than that of the control group(P<0.05).One month after treatment,the levels of regional cerebral bloodflow(rCBF)and regional cerebral blood volume(rCBV)in the observation group were higher than those in the control group,while the levels of mean transit time(MTT),peak systolic velocity(PSV),and pulsatility index(PI)were lower than those in the control group(P<0.05).The study found that compared with pharmacological treatment,endovascular stenting treatment for asymptomatic internal carotid artery stenosis has better clinical efficacy,can effectively increase cerebral bloodflow,improve cerebral hemodynamics,and has little impact on cognitive function.

关 键 词：无症状性颈内动脉狭窄 药物治疗 血管内支架治疗 临床疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]