Neuronal activities drive brain waste clearance through the glymphatic system  

作　　者：Lin-jian Wang Xiwen Ma Jianping Ye 

机构地区：[1]Institute of Trauma and Metabolism,Zhengzhou Central Hospital Affiliated to Zhengzhou University,Zhengzhou 450007,China [2]Tianjian Laboratory of Advanced Biomedical Sciences,Academy of Medical Sciences,Zhengzhou University,Zhengzhou 450001,China

出　　处：《Acta Pharmaceutica Sinica B》2025年第2期1193-1195,共3页药学学报(英文版)

基　　金：supported by the National Natural Science Foundation of China(Grant No.32271220).

摘　　要：Neurons are the main organizers of neurological activities in the brain.However,its role remains largely unknown in regulating waste clearance in the brain.This issue is addressed in a recent study published in Nature on neuronal dynamics in control of waste removal through cerebrospinal fluid perfusion1.Brain contains billions of neurons that are connected through synapses for precise spatial coordination and high-speed operation in support of functions like thoughts,emotions,and body movements in a dynamic manner.

关 键 词：Alzheimer disease NEURON Glymphatic system Cerebrospinal fluid perfusion Brain clearance 

分 类 号：R741[医药卫生—神经病学与精神病学]