Oral garlic-derived nanoparticles improve cancer immunotherapy  

作　　者：Kun Yang Jinming Zhang Bo Xiao 

机构地区：[1]State Key Laboratory of Resource Insects,College of Sericulture,Textile,and Biomass Sciences,Southwest University,Chongqing 400715,China [2]State Key Laboratory of Southwestern Chinese Medicine Resources,Pharmacy School,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China [3]Department of Pharmacy,Personalized Drug Therapy Key Laboratory of Sichuan Province,Sichuan Academy of Medical Sciences&Sichuan Provincial People’s Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu 610054,China

出　　处：《Acta Pharmaceutica Sinica B》2025年第2期1199-1201,共3页药学学报(英文版)

基　　金：supported by the National Natural Science Foundation of China(82072060);the Open Research Fund of State Key Laboratory of Southwestern Chinese Medicine Resources(SKLTCM2022067,China).

摘　　要：Gamma-delta(γδ)T cells exhibit tissue tropism and possess antitumor activity that is independent of new antigen load and traditional MHC-dependent antigen presentation.These cells also present characteristics typical of both T cells and natural killer cells1.The gastrointestinal tract is the largest immune organ in the human body,containing approximately 70%of the body's immune cells,including a substantial population ofγδT cells2,3.

关 键 词：Oral administration Garlic-derived nanoparticle Cancer IMMUNOTHERAPY 

分 类 号：R730.5[医药卫生—肿瘤]