竹酒体外体内抗氧化功能活性研究  

Analysis of antioxidant activity of bamboo wine in vitro and in vivo

作　　者：向诗银 王喆 杨强 施鹏 潘凯进 周俊强 徐剑 XIANG Shiyin;WANG Zhe;YANG Qiang;SHI Peng;PAN Kaijin;ZHOU Junqiang;XU Jian(Hubei Provincial Key Laboratory for Quality and Safety of Traditional Chinese Medicine Health Food,Jin Brand Co.,Ltd.,Huangshi 435100)

机构地区：[1]劲牌有限公司中药保健食品质量与安全湖北省重点实验室,黄石435100

出　　处：《中国食品添加剂》2025年第4期86-92,共7页China Food Additives

摘　　要：本研究以竹酒为研究对象,利用ORAC法和D-半乳糖诱导小鼠氧化损伤模型,对竹酒的体内体外抗氧化活性进行了研究,采用试剂盒对小鼠体内的PCO、SOD等生化指标进行检测。结果表明,在体外模型中竹酒抗氧化值为3863.259μmol TE/g;小鼠体内实验中,与模型组比较,天成竹酒和高纯度竹酒各个剂量组小鼠肝组织PCO及血清MDA含量均显著下降(P<0.05),小鼠肝组织SOD活性、肝组织GSH含量无显著变化,说明长期口服竹酒能够有效清除小鼠体内的自由基,减轻氧化应激损害,竹酒具有良好的抗氧化功能活性。In this study,bamboo wine was used as the research object,the antioxidant activity of bamboo wine in vivo and in vitro was investigated using ORAC method and D-galactose induced oxidative damage model in mice.Biochemical indicators such as PCO and SOD in the mice were detected using kits.The results showed that the antioxidant value of bamboo wine in the in vitro model was 3863.259μmol TE/g.In the in vivo experiment,compared with the model group,the PCO levels in liver tissue and MDA content in the serum of mice receiving various dosages of Tiancheng bamboo wine and high-purity bamboo wine significantly decreased(P<0.05).There were no significant changes in the SOD activity and GSH content in the liver tissues of the mice.Thesefindings suggested that long-term oral administration of bamboo wine can effectively remove free radicals in mice and reduce oxidative stress damage,indicating that Bamboo wine has good antioxidation functional activity.

关 键 词：竹酒 氧化应激 抗氧化 体内体外 

分 类 号：TS202.3[轻工技术与工程—食品科学]