A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior  

作　　者：Helmut Kettenmann 

机构地区：[1]Shenzhen University of Advanced Technology,Shenzhen,518055,China [2]Max-Delbrück Center for Molecular Medicine,13092,Berlin,Germany

出　　处：《Neuroscience Bulletin》2025年第2期352-354,共3页神经科学通报(英文版)

基　　金：supported by the Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases(ZDSYS20220304163558001).

摘　　要：A recent publication by Zhou et al.[1]in Neuron demonstrates that a specific interaction between astrocytes and a subtype of neurons has an influence on complex animal behavior,namely risk assessment.The majority of neuroscientists analyzing the molecular and cellular substrate of behavior focus on neuronal circuits.Glial cells were originally described by Rudolf Virchow and the name glia refers to the Greek word for glue or putty.Thus,glial cells were long thought to represent simply the filling stuff of the brain.This view has changed dramatically in the last decades.The three major types of glial cells of the central nervous system fulfll diverse functions.Oligodendrocytes are the myelinforming cells and it has become evident that they are plastic and are able to influence neuronal connectivity.Microglia are the immune cells of the brain and interact with synapses during development,in plasticity,and very prominently in any disease of the nervous system.

关 键 词：complex animal behavior NEURON glial cells molecular cellular substrate molecular cellular substrate behavior ASTROCYTE INTERACTION risk assessment 

分 类 号：R338[医药卫生—人体生理学]