GlycoRNA:A new player in cellular communication  

作　　者：HYUNG SEOK KIM 

机构地区：[1]Department of Biochemistry,Kosin University College of Medicine,Seo-gu,Busan,49267,Republic of Korea

出　　处：《Oncology Research》2025年第5期995-1000,共6页肿瘤学研究(英文)

基　　金：funded by the Korea Health Technology R&D Project through the Bio and Medical Technology Development Program of the National Research Foundation,supported by the Ministry of Science and ICT(RS-2023-00210847)and the Ministry of Education(RS-2024-00463331),Republic of Korea.

摘　　要：The discovery of glycosylated RNA molecules,known as glycoRNAs,introduces a novel dimension to cellular biology.This commentary explores the transformative findings surrounding glycoRNAs,emphasizing their unique roles in cancer progression and the therapeutic opportunities they present.GlycoRNAs,through interactions with lectins and immune receptors,may contribute to tumor immune evasion.Moreover,the therapeutic potential of this emerging knowledge includes interventions targeting glycoRNA synthesis and modulation of associated signaling pathways.By highlighting these critical insights,this commentary aims to encourage the development of innovative strategies that could improve cancer prognosis and treatment.

关 键 词：GlycoRNA Cancer biology GLYCOSYLATION Immune evasion Therapeutic targets RNA modifications Lectin interactions 

分 类 号：R730.2[医药卫生—肿瘤]