膳食纤维抗性糊精干预对多囊卵巢综合征患者代谢指标的影响  

Effects of dietary fiber resistant dextrin intervention on metabolism indicators in patients with polycystic ovary syndrome

作　　者：王晓晨 武聪娜 李艳[2] 方迎春[2] WANG Xiaochen;WU Congna;LI Yan;FANG Yingchun(Department of Clinical Nutrition,Sunshine Union Hospital,Weifang 261000,China;Department of Gynaecology,Weifang People's Hospital)

机构地区：[1]阳光融和医院临床营养科,山东潍坊261000 [2]潍坊市人民医院妇科

出　　处：《山东第二医科大学学报》2025年第1期47-50,共4页Journal of Shandong Second Medical University

基　　金：潍坊市科技发展计划项目(项目编号:2022YX151)。

摘　　要：目的 探讨膳食纤维抗性糊精对多囊卵巢综合征(PCOS)患者体重、体质量指数(BMI)、腰围及糖脂代谢指标、胰岛素抵抗水平和性激素水平的影响。方法 选取2023年1月~2023年12月我院收治的100例PCOS患者为研究对象,随机分为对照组和观察组,每组各50例。对照组给予常规饮食,观察组在常规饮食基础上给予膳食纤维抗性糊精干预。测量记录两组患者腰围、体重、体质量指数、收缩压(SBP)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、血尿酸(UA),采用化学发光法测定睾酮(TT)、空腹胰岛素(FIN),计算胰岛素抵抗指数(HOMA-IR),比较两组的差异。结果 干预后,两组患者的腰围、BMI、SBP均降低,且观察组低于对照组(P<0.05);TG、LDL-C、FBG、UA均降低,且观察组低于对照组(P<0.05);观察组HDL-C升高,升高幅度高于对照组(P<0.05);两组FIN、HOMA-IR和TT均降低,且观察组低于对照组(P<0.05)。结论 膳食纤维抗性糊精干预可改善PCOS患者的体重和代谢指标,减轻胰岛素抵抗,改善激素水平。Objective To explore the impacts of dietary fiber resistant dextrin intervention on body weight,body mass index(BMI),waist circumference,glucose and lipid metabolism parameters,insulin resistance,and sex hor-mone levels in patients with polycystic ovary syndrome.Methods A total of 100 patients with polycystic ovary syndrome admitted to the hospital were selected as the research subjects.These patients were randomly divided into a control group(50 cases,on a conventional diet)and an observation group(50 cases,with a conventional diet supplemented by dietary fiber resistant dextrin).Their waist circumferences,weights,BMI,systolic blood pressure(SBP),levels of triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),fasting blood glucose(FBG),blood uric acid(UA)were measured.The chemiluminescence method was employed to detect total testosterone(TT)and fasting plasma insulin(FIN),and HOMA-IR was calculated.The intervention effects of the two groups were then compared.Results After the intervention,the waist circumferences,weights,BMI,and SBP of both groups de-clined,and those in the observation group were significantly lower than those in the control group(P<0.05).Post-inter-vention,the levels of TG,LDL-C,FBG,and UA in both groups decreased,with the values in the observation group being lower than those in the control group(P<0.05).The HDL-C level in the observation group increased and was higher than that in the control group(P<O.05).After the intervention,fasting insulin,insulin resistance index(HOMA-IR),and TT of both groups decreased,and those in the observation group were lower than those in the control group(P<0.05).Conclusion Dietary fiber resistant dextrin intervention in patients with polycystic ovary syndrome can enhance body weight and metabolic indicators,relieve insulin resistance,and improve sex hormone levels.

关 键 词：膳食纤维 多囊卵巢 代谢指标 抗性糊精 

分 类 号：R711.75[医药卫生—妇产科学]