PathActMarker:an R package for inferring pathway activity of complex diseases  

作　　者：Xingyi LI Jun HAO Zhelin ZHAO Junming LI Xingyu LIAO Min LI Xuequn SHANG 

机构地区：[1]School of Computer Science,Northwestern Polytechnical University,Xi’an 710072,China [2]Research&Development Institute of Northwestern Polytechnical University in Shenzhen,Shenzhen 518063,China [3]School of Software,Northwestern Polytechnical University,Xi’an 710072,China [4]Hunan Provincial Key Lab on Bioinformatics,School of Computer Science and Engineering,Central South University,Changsha 410083,China

出　　处：《Frontiers of Computer Science》2025年第3期123-124,共2页计算机科学前沿(英文版)

基　　金：supported in part by the National Natural Science Foundation of China(Grant No.62202383);Guangdong Basic and Applied Basic Research Foundation(No.2024A1515012602);the National Key Research and Development Program of China(No.2022YFD1801200).

摘　　要：1 Introduction The process of complex diseases is closely linked to the disruption of key biological pathways,it is crucial to identify the dysfunctional pathways and quantify the degree of dysregulation at the individual sample level[1].

关 键 词：pathway activity DYSREGULATION complex diseases biological pathways disruption key biological pathwaysit identify dysfunctional pathways 

分 类 号：R73[医药卫生—肿瘤]