积极心理学干预在行血浆置换的多发性骨髓瘤伴高黏滞综合征患者中的应用效果  

Application effect of positive psychology intervention in patients with multiple myeloma complicated with hyperviscosity syndrome undergoing plasmapheresis

作　　者：黄思飞 朱礼阳 陈瑞斯 李炎生[2] HUANG Sifei;ZHU Liyang;CHEN Ruisi;LI Yansheng(Blood Purification Centre(2),the First Affiliated Hospital of Zhengzhou University,Zhengzhou 453000,He’nan,China;Second Ward,Kidney Internal Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 453000,He’nan,China)

机构地区：[1]郑州大学第一附属医院血液净化中心(2),郑州4530000 [2]郑州大学第一附属医院肾脏内科二病区,郑州4530000

出　　处：《癌症进展》2025年第9期1090-1093,共4页Oncology Progress

摘　　要：目的探讨积极心理学干预在行血浆置换的多发性骨髓瘤伴高黏滞综合征(HVS)患者中的应用效果。方法根据干预方式的不同将93例多发性骨髓瘤伴HVS患者分为对照组(n=40)和观察组(n=53),对照组患者接受常规干预,观察组患者在常规干预的基础上给予积极心理学干预。比较两组患者的负性情绪[汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)]、生活质量[生活质量综合评定问卷(GQOLI-74)]、并发症发生情况和依从性。结果干预后,两组患者HAMA、HAMD评分均低于本组干预前,观察组患者HAMA、HAMD评分均低于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的总依从率为92.45%,高于对照组患者的77.50%,差异有统计学意义(P﹤0.05)。干预后,两组患者GQOLI-74各维度评分均高于本组干预前,观察组患者GQOLI-74各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的并发症总发生率为5.66%,低于对照组患者的20.00%,差异有统计学意义(P﹤0.05)。结论积极心理学干预能够改善行血浆置换的多发性骨髓瘤伴HVS患者的负性情绪,提高生活质量和依从性,减少并发症发生风险。Objective To explore the application effect of positive psychology intervention in patients with multiple myeloma complicated with hyperviscosity syndrome(HVS)undergoing plasmapheresis.Method According to different intervention methods,93 patients with multiple myeloma complicated with HVS were divided into control group(n=40)and observation group(n=53).Patients in the control group received routine intervention,while patients in the observation group received positive psychological intervention on the basis of routine intervention.The negative emotions[Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD)],quality of life[generic quality of life inventory-74(GQOLI-74)],incidence of complications,and compliance were compared between the two groups.Result After intervention,the HAMA and HAMD scores in both groups were lower than those before intervention,the HAMA and HAMD scores in observation group were lower than those in control group,and the differences were statistically significant(P<0.05).The total compliance rate in observation group was 92.45%,which was higher than 77.50%in control group,and the difference was statistically significant(P<0.05).After intervention,the scores of dimensions of GQOLI-74 in both groups were higher than those before intervention,the scores of dimensions of GQOLI-74 in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).The total incidence of complications in observation group was 5.66%,which was lower than 20.00%in control group,and the difference was statistically significant(P<0.05).Conclusion Positive psychology intervention can improve the negative emotions of multiple myeloma patients complicated with HVS undergoing plasmapheresis,enhance quality of life and compliance,and reduce the risk of complications.

关 键 词：积极心理学 血浆置换 多发性骨髓瘤 高黏滞综合征 

分 类 号：R733.3[医药卫生—肿瘤]