循环压力法冻干兔角膜的实验研究  

Experimental Study of Freeze-drying Rabbit Cornea by Cyclic Pressure

作　　者：王德喜[1] 徐成海[1] 张世伟[1] 曹永梅[2] 

机构地区：[1]东北大学,沈阳110004 [2]中国医科大学第二临床医院,沈阳110003

出　　处：《真空科学与技术》2002年第6期450-453,458,共5页Vacuum Science and Technology

基　　金：国家自然科学基金资助项目 (No .5 98760 0 8)

摘　　要：通过不同压力下兔角膜真空冷冻干燥的实验研究 ,认为采用变幅值、变周期的循环压方法可以提高冻干兔角膜的活性。得出冻干循环压力法参数 :压力幅值 ,压力周期的优化是提高角膜活性的关键。Rabbit cornea was successfully freeze dried by cyclic pressure freeze drying.We suggest that the period and pressure amplitude in the cyclic pressure drying should be carefully optimized because these two key factors significantly affect the surviving rate of the rabbit cornea.

关 键 词：循环压力 冻干兔 真空冷冻干燥 角膜 冻干法保存 角膜移植 

分 类 号：R779.65[医药卫生—眼科] R318[医药卫生—临床医学]