细胞粘附分子CD_(18)、CD_(54)表达在急性脑梗塞中的意义  

Research on expression of cell adhesion molecules CD_(18),CD_(54) in patients with acute cerebral infarction(ICA)

作　　者：栾桂红[1] 徐维家[2] 刘玉英[1] 

机构地区：[1]大连市中心医院,辽宁大连116033 [2]大连市临床检验中心,辽宁大连116033

出　　处：《大连医科大学学报》2002年第4期278-279,共2页Journal of Dalian Medical University

摘　　要：[目的 ]探讨粘附分子CD18、CD54 粘附功能及其表达变化与急性脑梗塞 (ICA)关系。[方法 ]用流式细胞术检测 88例ICA患者白细胞粘附分子CD18、CD54 质量分数与脑梗塞治疗前后表达 ,并与 30例正常人作对照。[结果 ]ICA患者CD18、CD54 表达明显增高 ,与正常对照组比较差异显著 (P<0 .0 5 ) ,治疗前后比较CD18有显著性差异 (P <0 .0 5 )。[结论 ]CD18、CD54 参与脑梗塞发生发展病理过程 。To explore the relation of adhesion function and change of expression of cell adhesion molecules CD 18 ,CD 54 with acute cerebral infarction (ICA). In flow cell method(FCM), to detect expression of leukocyte adhesion molecules CD 18 ,CD 54 in 88 acute cerebral infarction patients with 30 controls, before and after treatment. The expression of CD 18 ,CD 54 was significantly raise, obviously different than the controls ( P >0.05). [Conclusion] CD 18 ,CD 54 might take part in occurrence of ICA pathology process. CD 18 ,CD 54 might take part in occurrence of ICA pathology process. CD 18 is a additional diagnosis index for ICA.

关 键 词：细胞粘附因子 CD18 CD54 脑梗塞 

分 类 号：R743.32[医药卫生—神经病学与精神病学]