慢性情绪应激对大鼠行为的影响及变化趋势  

The effect of chronic emotional stress on the behaviors of rats and its changing trend

作　　者：邵枫[1] 林文娟[2] 陈极寰[2] 

机构地区：[1]北京大学心理学系,北京100871 [2]中国科学院心理研究所脑-行为中心,北京100101

出　　处：《中国行为医学科学》2003年第1期5-6,17,共3页Chinese Journal of Behavioral Medical Science

基　　金：中科院知识创新工程项目 (Ksx2 2 0 3);教育部科学技术重点项目 ( 0 2 170 )

摘　　要：目的　探讨空瓶刺激诱发的慢性情绪应激对大鼠行为的影响及行为变化的趋势。方法　利用空瓶刺激诱发的情绪应激模型 ,观察记录连续 1 4次 ,每次 1 0分钟的情绪应激期间 ,情绪应激组、对照组和生理应激组大鼠的攻击性行为、探究行为和修饰行为的表现。结果　连续 1 4次的情绪应激期间 ,与对照组和生理应激组相比 ,情绪应激组大鼠均表现出明显的攻击性行为 ,而对照组和生理应激组大鼠仅表现为探究和修饰行为。结论　慢性情绪应激能诱发大鼠行为的明显改变 ,且这种行为的改变与应激频率无关。Objective To explore the effect of chronic emotional stress on the behaviors of rats and its changing trend. Method Utilizing the animal model of emotional stress induced by empty water bottles, rats were divided into three groups:emotional stress group, control group and physiological stress group. During 14 times emotional stress procedure, 10 minutes per time, attacking, exploring and grooming behaviors of rats in three groups were investigated and recorded. Results During 14 times emotional stress procedure, compared to rats in control and physiological stress groups, rats in emotional stress group always expressed significant attacking behavior, and rats in control and physiological stress groups expressed exploring and grooming behaviors. Conclusion During chronic emotional stress procedure, behaviors of rats in emotional stress group changed significantly, which was independent of stress frequency.

关 键 词：情绪应激 攻击性行为 探究行为 修饰行为 空瓶刺激 

分 类 号：R741.04[医药卫生—神经病学与精神病学]