对氨基苯甲酸对粘性放线菌表面疏水性的影响  

Effect of Para-aminobenzonic Acid on Cell-Surface Hydrophobicity of Actinomyces viscosus

作　　者：李继遥[1] 李艳红[1] 周学东[1] 肖晓蓉[1] 柳茜[1] 

机构地区：[1]四川大学华西口腔医学院,成都610041

出　　处：《四川大学学报（医学版）》2003年第3期491-493,共3页Journal of Sichuan University(Medical Sciences)

基　　金：国家自然科学基金 (批准号 39670 785 )资助

摘　　要：目的　研究血链球菌合成的生态调节因子——对氨基苯甲酸 ( PABA)对粘性放线菌细胞表面疏水性的影响 ,进一步了解 PABA影响细菌粘附的机制。方法　在含不同浓度 PABA( 10 - 9g/ L、10 - 7g/ L、10 - 4 g/ L)的改良Carlsson液体培养基中厌氧培养粘性放线菌 ,并采用微生物粘着碳氢化合物法 ( MATH)测试细胞表面疏水性。结果　随着培养基中 PABA浓度的增高 ,粘性放线菌细胞表面疏水性随之逐渐降低 ,其疏水率分别为 0 .3 890 0±0 .0 0 0 2 6,0 .2 5 462± 0 .0 0 168,0 .163 60± 0 .0 0 0 2 6( P均 <0 .0 5 )。结论　Objective To study the effect of Para-aminobenzonic acid(PABA) on cell-surface hydrophobicity of Actinomyces viscosus. Methods Microbial adhesion to hydrocarbons (MATH) was used to measure the cell-surface hydrophobicity of Actinomyces viscosus which grew in modified Carlsson medium with different dilution of PABA. Results Following the increase of concentration of PABA, the value of cell-surface hydrophobicity of Actinomyces viscosus decreased, which were 0.38900±0.00026, 0.25462±0.00168, 0.16360±0.00026 respectively(P<0.05). Conclusion PABA could inhibit the adherence of Actinomyces viscosus by way of changing its cell-surface hydrophobicity.

关 键 词：氨基苯甲酸 粘性放线菌 表面疏水性 影响 

分 类 号：R780.2[医药卫生—口腔医学]