家族性与散发性精神分裂症临床及智力功能的对照研究  

Comparative study of clinical features and intelligence between the patients with familial and sporadic schizophrenia

作　　者：高新学[1] 曾昭祥[1] 刘琳[1] 李志成[1] 

机构地区：[1]山东省济宁市精神病防治院,山东济宁272051

出　　处：《中国民康医学》2003年第8期451-452,455,共3页Medical Journal of Chinese People’s Health

摘　　要：目的 :比较家族性与散发性精神分裂症的临床及智力功能。方法 :根据CCMD - 2 -R诊断标准 ,对36例家族性精神分裂症和 76例散发性精神分裂症的临床特点及智力测验结果进行了对比分析。结果 :同散发性精神分裂症相比 ,家族性精神分裂症阴性症状相对突出、智力功能受损较重 (突出表现在领悟、相似性、词汇及图形拼凑等方面 )、疗效不佳。结论 :家族性精神分裂症阴性症状突出 ,智力功能受损较重 ,可能与其遗传学基础有关。Objective:To compare the clinical feature and intelligence between the patients with familial and sporadic schizophrenia.Methods:36 patients with familial schizophrenia and 76 patients with sporadic schizophrenia were diagnosed according to the CCMD-2-R classification The clinical features and intelligence were compared between the two groups Results:Comparing with the sporadic group,the familial group showed outstanding negative symptom,severe impairment of the intellective function(The distinct manifestation were comprehension,similarity,vocabulary and picture together )and unwell curative effect Conclusion:The outstanding negative symptom and severe impairment of the intellective functon in the familial schizophrenia patients suggested that it may be related to their gentics bases

关 键 词：家族性精神分裂症 散发性精神分裂症 智力测验 遗传学 临床特点 

分 类 号：R749.3[医药卫生—神经病学与精神病学]