Effects of“Moxibustion Serum”on Proliferation and Phenotypes of Tumor Infiltrating Lymphocytes  

作　　者：陈云飞 赵粹英 陈汉平 秦慧莲 方舫 王友京 

机构地区：[1]Shanghai Institute of Acupuncture & Meridians,Shanghai 200030 [2]Teaching and Research Section of Immunology,Shanghai Medical University

出　　处：《Journal of Traditional Chinese Medicine》2003年第3期225-229,共5页中医杂志（英文版）

摘　　要：Tumor infiltrating lymphocytes (TIL) were cultured with “moxibustion serum”(MS), and the results were examined by flow cytometry. The results indicated that MS could enhance the proliferation of TIL,accelerate it to reach the exponential growth phase, and assist recombinant interleukin 2 (rIL-2) to enhance successively the percentage of CD3^+ positive cells, maintain the number of CD4^+ positive T cells, promote greatly the percentage of CD8^+ positive T cells among TILs, and reverse the CD4^+/CD8^+ ratio. Such cooperative effects rely on relative specificity of acupoints. It is suggested that MS is beneficial to the growth of TIL both in the aspects of proliferation and phenotypes.Tumor infiltrating lymphocytes (TIL) were cultured with “moxibustion serum” (MS),and the results were examined by flow cytometry.The results indicated that MS could enhance the proliferation of TIL, accelerate it to reach the exponential growth phase,and assist recombinant interleukin 2 (rIL-2) to enhance successively the percentage of CD_3^+ positive cells,maintain the number of CD_4^+ positive T cells,promote greatly the percentage of CD_8^+ positive T cells among TILs,and reverse the CD_4^+/CD_8^+ ratio.Such cooperative effects rely on relative specificity of acupoints.It is suggested that MS is beneficial to the growth of TIL both in the aspects of proliferation and phenotypes.

关 键 词：ARTEMISIA Moxibustion Animals Antigens  CD3 Blood CD4-CD8 Ratio Cell Division Culture Media  Conditioned Drugs  Chinese Herbal Female INTERLEUKIN-2 Lymphocytes  Tumor-Infiltrating MICE Mice  Inbred C57BL Phenotype Recombinant Proteins Thymus Neoplasms Tumor Cells  Cultured 

分 类 号：R245[医药卫生—针灸推拿学]