壳聚糖的制备及降解工艺条件的选择  

The preparation of chitosan and the choice of NaNO_2 degrading conditions

作　　者：上官国莲[1] 张英慧[1] 董华强[1] 蔡志宁[1] 阮少艺[1] 廖均成[1] 

机构地区：[1]佛山科学技术学院食品科学系,广东佛山528000

出　　处：《佛山科学技术学院学报（自然科学版）》2003年第3期47-49,共3页Journal of Foshan University(Natural Science Edition)

摘　　要：本文探讨了壳聚糖的制备方法及使用NaNO_2降解法制备低聚壳聚糖的工艺条件。采用酸碱水解的方法制得壳聚糖,并对其理化性质进行了检测;同时采用正交试验设计探讨了降解条件对产物特征粘度和粘均分子量的影响。试验结果表明,各降解条件对壳聚糖粘均分子量的影响大小为:反应时间>反应温度>10％NaNO_2用量>乙酸浓度,最佳处理为:10％NaNO_2的用量0.6mL,反应温度40℃,反应时间45min,乙酸浓度1％。The commonly used preparation method of chilosan and the conditions of degradation with NaNO2 are mainly discussed. We get chitosan by acid and alkali hydrolysis method, and detect its physiochemical properties. The effects of degradation conditions on the average viscosimetric molecular weight and intrinsic viscosity of chitosan are also studied. The factors of degrading conditions on the average viscosimetric molecular weight have different importance-reaction time> reaction temperature>dose of 10% NaNO2> CH3COOH concentration, and the best treatment is : 0. 6 ml 10% NaNO2,40 Creaction temperature,45 min reaction time and 1% CH3COOH concentration.

关 键 词：壳聚糖 NaNO2 降解 脱矣酰度 特征粘度 

分 类 号：Q539[生物学—生物化学]