从绿鳍马面鲀鱼油中分离制备高纯度二十二碳六烯酸甲酯  

THE PREPARATION OF HIGH-PURITY METHYL ESTER OF DOCOSAHEXAENOIC ACID FROM THE OIL OF NAVODON SEPTENTRIONALIS GüNTHER

作　　者：刘冬[1] 洪盈 陈光文[2] 王圣符[2] 宋宏锐[2] 

机构地区：[1]内蒙古医学院药学系 [2]沈阳药学院有机化学教研室

出　　处：《沈阳药学院学报》1992年第4期250-254,共5页

摘　　要：现代医学证明,二十碳五烯酸和二十二碳六烯酸具有多种生物活性。本文报道:通过综合运用金属盐沉淀法、尿素包合法、真空蒸馏法以及反相液相层析法从绿鳍马面纯鱼油中分离得到95%纯度的DHA甲酯。Modern medical science has proved that 5,8,11,14,17-all-cis eicosapentaenoic acid (EPA) and 4,7,10,13,16,19-all-cis docosahexaenoic acid (DHA) have many different biological activities. This paper reports how methyl ester of DHA of 95% purity was obtained from the oil of Navodon Septentrionalis Cunther by combining the techniques of salt crytallization, urea inclusioncomplex, vaccum distillation and reversedphase liquid chromatography.

关 键 词：鱼油 尿素 二十二碳烯酸 绿鳍马面Tun 分离 制备 

分 类 号：R914.4[医药卫生—药物化学]