软组织纤维肉瘤根治术后联合放疗59例  

Surgical Therapy Combined with Radiotherapy in 59 Cases with Fibrosarcoma

作　　者：周光华[1] 雷衍凡[2] 尹时生[1] 

机构地区：[1]解放军163医院,湖南长沙410003 [2]中南大学湘雅医院,湖南长沙410008

出　　处：《肿瘤学杂志》2003年第6期322-323,共2页Journal of Chinese Oncology

摘　　要：[目的]探讨手术切除联合外照射在治疗软组织纤维肉瘤及预防复发中的疗效。[方法]110例软组织纤维肉瘤分为单纯手术根治组(51例)及手术根治后加放疗组(59例),放疗采用钴60鄄γ线与深部X线混合照射。[结果]手术根治组5年生存率60.8%,10年生存率43.1%,5年内复发率60.8%,远处转移率33.3%;术后放疗组5年生存率79.7%,10年生存率59.3%,5年局部复发率13.6%,远处转移率15.3%;两组比较5年生存率及远处转移率存在显著差异(P<0.05),5年复发率亦存在显著差异(P<0.001),10年生存率无明显差异。[结论]纤维肉瘤易复发,术后放疗能提高生存率,降低复发率。To evaluate the effect of surgic al therapy combined with radiotherapy on treatment and recurrent prevention for fibrosarcoma.One hundred and ten patients with soft tissue fibrosarcoma were divided into surgical therapy(ST)group(51cases)and surgical therapy combin ed with radiotherapy(ST+RT)group(59cases).re used in radiotherapy.The5-and10-year su rvival rates of ST group were60.8%,43.1%and those of group(RT+ST)were79.7%,59.3% ,respectively.The5-year recurrent rates of ST group and ST+RT group were60.8%an d13.6%,respectively.The metatastic rates of ST group and ST+RT group were33.3%an d15.3%,respectively.The5-year survival rate of ST+RT group was significantly hi gher than that of ST group(P<0.05).The5-year recurrent rate and metastatic r ate of ST+RT group was significantly lower than that of ST group(P<0.001and P<0. 05).[Conclusions]Surgical therapy followed by radiotherapy can improve survivals of patients with fibrosarcoma and reduce the risk of recurrence.

关 键 词：纤维肉瘤 软组织肿瘤 外科学 放射疗法 

分 类 号：R738.6[医药卫生—肿瘤] R730.55[医药卫生—临床医学]